Science AI Journal
Medicine · Research topic

Open research questions in Organ Donation and Transplantation

115 unresolved questions extracted from the limitations and future-work sections of 887 Organ Donation and Transplantation papers in our library. Each links back to the study that raised it.

What the literature leaves open

  • The paper identifies the risk of prolonged warm or rewarming ischemia, vascular complications, conversion, graft dysfunction, or donor harm as a challenge in robotic transplantation. The paper also identifies the need to distinguish between bibliometric findings and clinical interpretation as a challenge. The paper notes that concentrated expertise can limit external validity and that outcomes from high-volume programs may not reproduce in lower-volume settings.

    Learning curves and training in robotic organ transplantation: bibliometric mapping with kidney transplantation as the principal clinical model · 2026 · DOI

  • Outcomes from high-volume programs may not reproduce in lower-volume settings, - early series may use favorable case selection, - unsuccessful program starts are less likely to be published, - external validity is limited

    Learning curves and training in robotic organ transplantation: bibliometric mapping with kidney transplantation as the principal clinical model · 2026 · DOI

  • The study identifies the challenge of navigating complex moral tensions related to consent, faith, responsibility, and communal expectations. Participants described feelings of invisibility, emotional burden, and limited institutional recognition of their supportive role. The study also highlights the challenge of balancing external support and internal experience, as communities were described as generous in instrumental help but emotionally inattentive or even spiritually coercive.

    Living Kidney Donation in Israel: The Lived Experiences of Donors’ Partners in Faith-Based Communities · 2026 · DOI

  • The perspectives of spouses of altruistic kidney donors remain largely overlooked within healthcare systems and religious discourse. There is a need for a more relational and ethically nuanced understanding of altruism in faith-based contexts. The study identifies a gap in the understanding of how individual, relational, communal, and institutional contexts shape spouses' experiences of donation.

    Living Kidney Donation in Israel: The Lived Experiences of Donors’ Partners in Faith-Based Communities · 2026 · DOI

  • where faith and religion go after playing a significant role in the decision to become an organ donor, - further studies on the connection between religion and living organ donations

    Living Kidney Donations in Israel: The Changing Impact of Religiosity · 2026 · DOI

  • The connection between religion and living organ donation is largely unexplored. Most existing studies have focused on the impact of religion on deceased organ donation.

    Living Kidney Donations in Israel: The Changing Impact of Religiosity · 2026 · DOI

  • Investigating the reasons behind the differences in consent rates among different religious and sociodemographic groups, - Examining the effectiveness of different strategies to increase consent rates, - Studying the impact of donor card registration on consent rates in different cultural and societal contexts

    Factors affecting family consent to corneal donation at a hospital-based eye bank in a tertiary Israeli medical center · 2026 · DOI

  • Limited understanding of factors affecting family consent to corneal donation in a culturally diverse setting. Need for identification of factors associated with consent to inform strategies for increasing donor tissue availability.

    Factors affecting family consent to corneal donation at a hospital-based eye bank in a tertiary Israeli medical center · 2026 · DOI

  • Gaps in laws regarding the disposal of property, bodies, and privacy of personal health data after a person's death, - Lack of guidance for those tasked with making decisions about involvement of a donor in research activities, - The guidelines may not be applicable in all jurisdictions

    The INTEGRITY guidelines – ethical guidance for research involving deceased donation and transplantation · 2026 · DOI

  • The lack of ethical guidance for research involving deceased donation and transplantation. The need for a normative foundation for ethical practice in this area. The complexity of ethical challenges in research involving deceased donation and transplantation.

    The INTEGRITY guidelines – ethical guidance for research involving deceased donation and transplantation · 2026 · DOI

  • Investigating the actual registration and donation rates among university students in the UAE, - Examining the effectiveness of different strategies to increase public awareness about brain death and organ donation, - Studying the attitudes and willingness to donate organs among different demographic groups in the UAE

    Attitudes toward organ donation among university students in the United Arab Emirates: a cross-sectional survey · 2025 · DOI

  • There is a lack of knowledge about university students' willingness to donate organs in the UAE. The study aims to address the gap in understanding the factors associated with willingness to donate organs after death.

    Attitudes toward organ donation among university students in the United Arab Emirates: a cross-sectional survey · 2025 · DOI

  • CONCLUSIONS: Most medical students in China had insufficient knowledge about brain death.

    Medical students’ knowledge and attitude toward brain death and the influence of medical education: a cross-sectional study · 2024 · DOI

  • BACKGROUND: The medical students' knowledge and attitude toward brain death has not been investigated in China.

    Medical students’ knowledge and attitude toward brain death and the influence of medical education: a cross-sectional study · 2024 · DOI

  • Background: The increasing prevalence of chronic diseases in Saudi Arabia has heightened the need for organ transplantation; however, the donor pool remains insufficient.

    Awareness and Willingness towards Organ Donation among Riyadh Residents: A Cross-Sectional Study · 2024 · DOI

  • Many studies rely on datasets that contain only basic donor and recipient attributes such as age, gender, and blood group, while important medical parameters and genetic compatibility factors are often missing. Most available datasets are relatively small and imbalanced, which affects the reliability and generalization capability of machine learning models. The limited use of genetic compatibility information such as Human Leukocyte Antigen (HLA) matching is a significant gap.

    Machine-Learning Based Organ Matching Prediction System · 2026 · DOI

  • Further research is needed to improve the accuracy and reliability of machine learning models in organ matching prediction. The use of genetic compatibility information such as Human Leukocyte Antigen (HLA) matching should be explored. The development of more efficient and effective organ allocation systems is necessary.

    Machine-Learning Based Organ Matching Prediction System · 2026 · DOI

  • Poor knowledge and misunderstanding of eye donation. Lack of technical knowledge and willingness to donate eyes. Cultural, religious, and informational obstacles to eye donation.

    Knowledge and Attitude Practices Regarding Eye Donation among University Students of Lahore: A Cross-Sectional Institution-Based Study · 2026 · DOI

  • Future studies can investigate the impact of educational interventions on enhancing awareness and intentions to donate eyes. Future studies can explore the factors that influence willingness to donate eyes among different populations. Future studies can develop and test interventions to improve knowledge and promote eye donation.

    Knowledge and Attitude Practices Regarding Eye Donation among University Students of Lahore: A Cross-Sectional Institution-Based Study · 2026 · DOI

  • There is a lack of awareness of rare anatomical variations during organ retrieval. The literature on supernumerary arteries and their impact on organ transplantation is limited.

    Abnormal kidney in deceased donor multiorgan retrieval: a case report · 2026 · DOI

  • There is a lack of understanding of the factors associated with attitudes towards organ donation in specific cultural contexts. Prior studies have identified factors associated with attitudes towards organ donation, but there is a need for further research in this area.

    Actitudes frente a la donación de órganos en población adulta de Chiclayo, Perú, 2025 · 2026 · DOI

  • Further studies should investigate the costs of kidney transplant in other countries. Further studies should compare the costs of different types of kidney transplant.

    Características clínicas y análisis integral de costos directos médicos y no médicos previos al trasplante renal en Colombia · 2026 · DOI

  • The lack of a structured ethical and clinical decision framework for rescue liver transplantation in patients with extrahepatic metastases. The need for a multidisciplinary team approach to guide the decision-making process.

    Rescue liver transplantation for liver failure with extrahepatic metastases: An ethical and clinical framework informed by two cases · 2026 · DOI

  • The decision to become a living organ donor is complex and influenced by various factors. The study's findings highlight the importance of considering the physical and emotional well-being of living donors. There is a need for further research on the decision-making, regret, and quality of life in living organ donors.

    Decision-making, regret, and quality of life in living organ donors: a cross-sectional study · 2026 · DOI

  • There is a lack of understanding of the factors influencing donation decisions and the outcomes for living donors. Prior studies have reported mixed findings on the outcomes for living donors. There is a need for further research on the decision-making, regret, and quality of life in living organ donors.

    Decision-making, regret, and quality of life in living organ donors: a cross-sectional study · 2026 · DOI

Most-cited papers in Organ Donation and Transplantation

Most recent work

Find a gap in your own Organ Donation and Transplantation sub-topic

This page shows what the Organ Donation and Transplantation literature already flags as unresolved. To narrow it to your specific question, run the guided finder — it searches the gap library on demand and checks candidates against 250M+ OpenAlex works.

Open the Research Gap Finder →

Related topics in Medicine

Artificial Intelligence in Healthcare and Education
2,044 open questions
Substance Abuse Treatment and Outcomes
1,964 open questions
Smoking Behavior and Cessation
990 open questions
Dementia and Cognitive Impairment Research
974 open questions
Innovations in Medical Education
960 open questions
Physical Activity and Health
923 open questions
Attention Deficit Hyperactivity Disorder
839 open questions
Schizophrenia research and treatment
709 open questions
115 open questions have been extracted from the limitations and future-work passages of 887 Organ Donation and Transplantation papers in our library. Each one below links back to the study that raised it, so you can read the original claim in context.

Tools for your next paper

Gaps & Literature SearchFind open questions in any field — 120,000+ open gaps mined from our own library.Pre-CheckIs your paper ready? A Tier 1–5 acceptance probability in seconds.Journal FinderA ranked shortlist of target journals from a 17,500-venue index.Duplicate Publication CheckerCheck prior-publication & salami-slicing risk across 8 sources.Citation GeneratorFreeA DOI or title → APA, MLA, Vancouver, Chicago, BibTeX, RIS. No signup.Graphical Abstract MakerFreeTurn your findings into a colorblind-safe graphical abstract.

Compare the category — Honest roundups of the AI research tools, ours listed alongside the alternatives.

Command palette

Jump anywhere, run any action.