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Open research questions in Pelvic floor disorders treatments

506 gap statements mined from Pelvic floor disorders treatments papers in our 7.9M-paper local library, which holds 2,352 papers on the topic — drawn mostly from each paper's own stated research gap, future-work, challenge and limitation notes, and its abstract. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one.

Choosing where to publish on Pelvic floor disorders treatments? See the ranked Medicine journals.

What the literature leaves open

  • The treatment gap requires International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF) score ≥ 8, daily pad/diaper use, pad/diaper-only management, and no active treatment in the previous 12 months.

    Treatment Gaps in Women Aged 65 Years and Older with Stress or Stress-Predominant Mixed Urinary Incontinence: Age-Stratified Patterns of Active Therapy, Containment Use, Frailty, and Anxiety · 2026 · DOI

  • There is a lack of studies on the prevalence of UI in women with SLE. The associated factors of UI in women with SLE are not well understood. Prior studies have reported inconsistent findings on the prevalence of UI in women with SLE.

    Prevalence of Urinary Incontinence and Associated Factors in Women with Systemic Lupus Erythematosus: A Cross-Sectional Study · 2026 · DOI

  • There is a need to examine the association between multimodal pelvic floor rehabilitation and improvements in low back pain, functional disability, and constipation-related symptoms among postpartum women. The study aims to address this gap by using a retrospective cohort design and including 352 postpartum women who underwent rehabilitation assessment.

    Association between multimodal pelvic floor rehabilitation and symptom improvement in postpartum women with low back pain and constipation: a retrospective cohort study · 2026 · DOI

  • The study identifies technical challenges in measuring sphincter fatigability, including the need for a standardized approach. The study notes the challenge of distinguishing between patients with fecal incontinence and healthy volunteers based on manometric parameters.

    Systematic Evaluation of External Anal Sphincter Fatigability in Healthy Women and Women With Fecal Incontinence: A High-Resolution Anorectal Manometric Study · 2026 · DOI

  • Future research should focus more on risk assessment tools and specific preventive measures for POUR following pelvic floor surgery.

    Urinary Retention Complications Following Pelvic Floor Reconstructive Surgery: Prevention and Management Strategies Based on Evidence Synthesis · 2026 · DOI

  • Pelvic‐organ prolapse (POP) is an age‐associated disorder that is often accompanied by uterosacral ligament (USL) weakening and extracellular matrix (ECM) degradation; however, the upstream regulators linking fibroblast aging to ECM remodeling remain incompletely defined.

    LncRNA FLJ20021 Restrains Fibroblast Senescence and Matrix Remodeling in Pelvic Organ Prolapse by Promoting XRCC6‐Dependent ADI1 Transcription · 2026 · DOI

  • Endovaginal electrostimulation is a well-established conservative therapy; however, the optimal stimulation frequency remains uncertain, particularly as a preventive measure in healthy populations.

    Comparative efficacy of low- vs. high‐frequency endovaginal electrostimulation combined with pelvic floor muscle training on pelvic floor bioelectrical activity in young, healthy women: a preliminary, single-center, randomized controlled trial · 2026 · DOI

  • Modified allostatic load (MAL) integrates adiposity, blood pressure, glucose-lipid metabolism, and inflammation, but its association with SUI remains unclear.

    Modified allostatic load and stress urinary incontinence in women: Evidence from a hospital-based cohort and NHANES · 2026 · DOI

  • The principal significant associations showed little or no between-stratum heterogeneity, suggesting a consistent direction of association across surgical approaches, although the limited number of subgroups (k = 3) and instances of non-estimable models restrict definitive conclusions regarding reproducibility; further validation in larger cohorts is warranted.

    Toward a Cross-Pathway Susceptibility Profile for Urinary Tract Infection After Pelvic Floor Reconstruction · 2026 · DOI

  • Prospective randomized controlled trials are warranted to confirm these findings.

    Pelvic floor magnetic stimulation combined with biofeedback-based electrical stimulation for obstructed defecation syndrome: a retrospective cohort study · 2026 · DOI

  • In Benin, data from physical medicine and rehabilitation (PMR) settings remain scarce.

    Incontinence Urinaire de la Femme au Bénin : Étude Mixte Rétrospective et Prospective des Facteurs Associés à l’Évolution | · 2026 · DOI

  • There is a lack of studies including both pre and postmenopausal women. Previous data showed an increased risk of developing urinary incontinence in breast cancer patients, but the association with age, co-diagnoses, and endocrine therapy is not well understood.

    Five-Year Incidence of Urinary Incontinence in 68,066 Breast Cancer Patients Followed in Gynecology Practices in Germany · 2025 · DOI

  • Where a lack of evidence was identified, expert opinion of the FNUU Executive Committee and a modified Delphi approach was utilised.

    British Association of Urological Surgeons (BAUS) consensus document on post‐prostatectomy incontinence‐stress urinary incontinence · 2025 · DOI

  • Intravaginal devices that support pelvic structures may offer a solution, but high-quality evidence is lacking.

    Intravaginal devices for running‐induced urinary incontinence symptoms in females: a study protocol · 2025 · DOI

  • However, the influence of urinary incontinence (UI), sexual dysfunction, and depressive symptoms on HRQoL across the first postpartum year remains unclear.

    The Impact of Urinary Incontinence, Sexual Dysfunction, and Depressive Symptoms on Health-Related Quality of Life Over the 12-Month Postpartum Period · 2025 · DOI

  • Synthetic mesh has been well established for abdominal soft tissue repair and in enhancing pelvic floor muscle tension in patients with pelvic organ prolapse; however, its role in sacrectomy has not been well documented.

    Synthetic Mesh Reconstruction Improves Pelvic Floor Function and Quality of Life After Sacrectomy: A Preliminary Clinical Assessment · 2025 · DOI

  • Although increasingly appreciated, little is known about the prevalence of fecal urgency, fecal incontinence and differences between patients' and physicians' perception in inflammatory bowel disease (IBD).

    Fecal urgency and incontinence in inflammatory bowel disease perceived by physician and patient: Results from the Swiss fecal urgency survey · 2024 · DOI

  • There remains a lack of consensus on who is responsible for the repair of these injuries.

    WP7.5 - Primary Repair of Obstetric Anal Sphincter Injuries (OASIS): a Survey of Surgeons’ Experience · 2024 · DOI

  • Limited evidence on the diagnostic value of the sagittal and transverse views. Technical challenges in obtaining high-quality images.

    Are Two Planes Better Than One?: A Comparative Analysis of Transverse versus Sagittal Pelvic Views in the FAST Examinations · 2026 · DOI

  • The study had a small sample size of six women. The clinical wear time was primarily limited by how long secure adhesion of the sensor to the body can be maintained. Flow rates exceeding 40 mL/s occasionally caused a detachment of the device. The system is technically capable of longer-term signal monitoring, but clinical wear time was limited. Only leakage measurements on three subjects were available.

    Wearable Personal Uroflowmeter for Measuring Urine Leakage in Women with Incontinence: Feasibility Study · 2025 · DOI

  • Limited accuracy and reliability of existing devices under dynamic conditions.

    Improving the Accuracy of a Wearable Uroflowmeter for Incontinence Monitoring Under Dynamic Conditions: Leveraging Machine Learning Methods · 2025 · DOI

  • Employing a larger-diameter urine channel in those women with urge urinary incontinence. Addressing the challenges for measurement in patients with urge urinary incontinence. Improving the adhesion of the sensor to the body. Increasing the sample size to validate the results. Exploring the use of wearable uroflowmetry to monitor leakage episodes in women with SUI.

    Wearable Personal Uroflowmeter for Measuring Urine Leakage in Women with Incontinence: Feasibility Study · 2025 · DOI

  • Further research is needed to understand the barriers to active treatment in older women with urinary incontinence, - Studies should investigate the effectiveness of different treatment approaches in this population, - Research should also examine the impact of frailty and functional dependence on treatment…

    Treatment Gaps in Women Aged 65 Years and Older with Stress or Stress-Predominant Mixed Urinary Incontinence: Age-Stratified Patterns of Active Therapy, Containment Use, Frailty, and Anxiety · 2026 · DOI

  • Further studies are needed to isolate the independent biological contribution of individual components of multimodal rehabilitation, - Studies should be conducted to evaluate the long-term effects of multimodal pelvic floor rehabilitation, - Research should be done to compare the effectiveness of different rehabilitation…

    Association between multimodal pelvic floor rehabilitation and symptom improvement in postpartum women with low back pain and constipation: a retrospective cohort study · 2026 · DOI

  • Further research is needed to investigate the relationship between endocrine therapy and urinary incontinence, - Studies examining the effect of different doses and durations of endocrine therapy on urinary incontinence are required, - Research on the impact of concomitant use of gonadotropin-releasing hormone (GnRH) analogs on urinary incontinence…

    Five-Year Incidence of Urinary Incontinence in 68,066 Breast Cancer Patients Followed in Gynecology Practices in Germany · 2025 · DOI

Most-cited papers in Pelvic floor disorders treatments

Most recent work

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Open questions raised by papers listed on this page include: (1) There is a lack of studies on the prevalence of UI in women with SLE (“Prevalence of Urinary Incontinence and Associated Factors in Women with…”, 2026); (2) There is a need to examine the association between multimodal pelvic floor rehabilitation and improvements in low back pain, functional disability, and constipation-related symptoms among postpartum women (“Association between multimodal pelvic floor rehabilitation and symptom…”, 2026); (3) Future research should focus more on risk assessment tools and specific preventive measures for POUR following pelvic floor surgery (“Urinary Retention Complications Following Pelvic Floor Reconstructive Surgery:…”, 2026); (4) Modified allostatic load (MAL) integrates adiposity, blood pressure, glucose-lipid metabolism, and inflammation, but its association with SUI remains unclear (“Modified allostatic load and stress urinary incontinence in women: Evidence…”, 2026); (5) Prospective randomized controlled trials are warranted to confirm these findings (“Pelvic floor magnetic stimulation combined with biofeedback-based electrical…”, 2026). 506 gap statements have been mined from Pelvic floor disorders treatments papers in our 7.9M-paper local library, which holds 2,352 papers on the topic; the gaps come from whichever of those papers state one. They are mostly the research gaps the authors state and the papers' abstracts, plus future-work, limitations and challenges passages. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one, so you can read the original claim in context.

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