Open research questions in Radiation Dose and Imaging
213 gap statements mined from Radiation Dose and Imaging papers in our 7.9M-paper local library, which holds 1,581 papers on the topic — drawn mostly from each paper's own stated research gap, future-work, challenge and limitation notes, and its abstract. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one.
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What the literature leaves open
One challenge identified in the study is the potential for variability in radiation exposure due to differences in surgeon practice patterns. Another challenge is the need to balance the reduction of radiation exposure with the maintenance of sufficient image quality for orthopedic procedures.
50% reduction of intraoperative radiation in orthopedics: impact of using the fluoroscopy’s lowest possible radiation settings · 2026 · DOIThere is a lack of understanding of the health effects of low doses of ionizing radiation. Prior studies have focused on high-dose acute radiation exposures, introducing uncertainties when extrapolating to lower doses. There is a need for epidemiological studies of low radiation exposures in large occupational cohorts.
Occupational radiation exposure and cause-specific mortality in a cohort of Canadian medical workers · 2026 · DOIThe prospective evaluation of these algorithms within routine clinical practice is warranted in future clinical studies.
Exploring a Novel Processing Algorithm to Improve Image Quality and Reduce X-Ray and Contrast Dose for Coronary Angiography: A Blinded Pilot Study · 2026 · DOIIt takes courage to admit when the status quo isn’t good enough, especially in health care, where so much has been accomplished but so much more remains to be done.
Leading by Example: Arizona’s Bold Step for Safer Catheterization Laboratories to Protect Our Doctors and Nurses · 2026 · DOIRoutine use of computed tomography (CT) in preoperative planning remains controversial due to concerns about radiation exposure and long-term oncogenic risk.
Preoperative computed tomography in femoroacetabular impingement is associated with increased risk of malignancy and other radiation‐associated pathologies · 2026 · DOIThe contribution of high radiation dose outliers to cumulative occupational radiation dose is understudied.
Relative Contribution of High-Dose Outliers to Cumulative Occupational Radiation Dose in the Catheterization Laboratory · 2025 · DOIRecent innovations like the Rampart M1128 enhanced radiation protection system (Rampart IC) aim to reduce these risks, but their impact on door-to-balloon (D2B) time in ST-elevation myocardial infarction (STEMI) has not been evaluated.
Impact of a Novel Radiation Protection System on Door-to-Balloon Time During STEMI Intervention · 2025 · DOIFurther studies are needed to validate the proposed dosage model in larger patient populations. Research is needed to develop pregnancy-specific dosing guidelines for [18F]FDG PET/CT imaging. Studies should investigate the potential variations in patient physiology and radiotracer uptake.
Smart scanning for two: [18F]FDG dose optimization for pregnant patients using LAFOV PET/CT technology · 2026 · DOIThere is a lack of dosimetric data on radiation exposure levels in diagnostic X-ray facilities in Nigeria. Previous studies have limited generalizability due to regional variations in radiation exposure levels.
Radiation Protection Practices in Classified Versus Non-Classified Areas of X-Ray Units in Jos Plateau State · 2026 · DOIFurther studies can investigate the effects of radiation exposure on human health in different populations. Further studies can explore the relationship between radiation exposure and cancer risk.
Measurements of Background Ionizing Radiation Levels in Selected Farms in Agbor, Delta State, Nigeria · 2026 · DOIThere is a need to measure background ionizing radiation levels in different geographical locations. There is a need to calculate health risks associated with radiation exposure in different populations.
Measurements of Background Ionizing Radiation Levels in Selected Farms in Agbor, Delta State, Nigeria · 2026 · DOIThe volume weighted computed tomography dose index does not account for differences in patient size. There is a need to evaluate the relationship between size-specific dose estimate and volume weighted computed tomography dose index with patient size for CT scanners.
Study of displayed radiation dose and size-specific dose estimate from computed tomography brain examinations in accordance to head sizes · 2026 · DOIThe lack of knowledge about interventional radiology and its associated radiation risks among the public and healthcare practitioners. The need for increased awareness and education about interventional radiology and radiation risks.
Awareness of Interventional Radiology and The Associated Radiation Exposure Risk Among The Public Population and Primary Care Physicians in Saudi Arabia · 2026 · DOIThere is a need to measure and evaluate the x-ray radiation dose received during diagnostic radiographic examinations in medical centers. There is a need to determine whether the radiation doses used in medical centers comply with internationally accepted radiation safety limits.
Radiation Dose Assessment In Diagnostic Radiography: A Case Study From A Medical Center In Qalqilya City, Palestine · 2026 · DOIThe need for regular QC testing, improved access to appropriate phantoms, and enhanced technical expertise in radiology departments in Albania. The lack of acceptance criteria for CT scanner image quality in Albania.
IMAGE QUALITY EVALUATION FOR COMPUTED TOMOGRAPHY MODALITIES BY MEDICAL PHYSICISTS AND IMAGING TECHNOLOGISTS IN VARIOUS HOSPITALS IN ALBANIA · 2026 · DOIThe two main limitations of this study are that the radiation doses employed were published average effective doses for newborns obtained from is a retrospective observational study of NICU infants.
Radiation exposure in neonatal intensive care unit of tertiary care hospital: a retrospective study · 2026 · DOIThe NDR database did not include the retirement date of a worker. Approximately 8% of workers remained unmatched due to incomplete or missing data required for the linkage. The NDR does not maintain records of organ-specific absorbed doses. Reliable reconstruction of organ-specific absorbed doses was not feasible due to unavailable key exposure parameters.
Occupational radiation exposure and cause-specific mortality in a cohort of Canadian medical workers · 2026 · DOIFew studies have investigated the potential modifying effects of age, sex, and other major CeVD risk factors.
Low-to-moderate dose ionizing radiation and cerebrovascular disease mortality in U.S. radiologic technologists, 1983-2021 · 2026 · DOIA few studies have reported increased CeVD risks at doses <500 mGy, but none of these provided data on CeVD risks by subtype.
Low-to-moderate dose ionizing radiation and cerebrovascular disease mortality in U.S. radiologic technologists, 1983-2021 · 2026 · DOIInadequate shielding can permit radiation scatter into supervised areas. Limited availability of dosimetric data on radiation exposure levels in diagnostic X-ray facilities. Ensuring continuous radiation monitoring and regular quality assurance programs.
Radiation Protection Practices in Classified Versus Non-Classified Areas of X-Ray Units in Jos Plateau State · 2026 · DOIThe study was conducted in a single region, Saudi Arabia. The sample size was limited to 625 respondents.
Awareness of Interventional Radiology and The Associated Radiation Exposure Risk Among The Public Population and Primary Care Physicians in Saudi Arabia · 2026 · DOIFurther studies are needed to investigate the long-term effects of reduced radiation exposure on orthopedic surgeons and staff, - Research on the application of LPR mode in other medical specialties is warranted, - Studies comparing different fluoroscopy systems and their radiation reduction capabilities…
50% reduction of intraoperative radiation in orthopedics: impact of using the fluoroscopy’s lowest possible radiation settings · 2026 · DOIFurther studies could investigate the effects of technical, geometric, shielding, and workflow factors on occupational radiation exposure, - Research could focus on developing strategies to minimize radiation exposure in fluoroscopy-guided procedures, - Studies could explore the application of real-time personal dosimetry in other medical…
Real-time occupational radiation dosimetry in anesthesiology personnel during fluoroscopy-guided interventions: a single-center descriptive and exploratory study · 2026 · DOIThis study highlights the necessity for additional research on intraoperative radiation doses, emphasising the importance of minimising radiation exposure in this vulnerable patient cohort.
Analysis of intraoperative radiation exposure in paediatric orthopaedic and trauma patients: a comparative cohort study · 2025 · DOIThe study identifies a gap in the comparison of the radiation effective dose of abdominal CT examination calculated by different methods. The study highlights the importance of estimating the radiation effective dose in CT examinations.
Estimation of radiation effective dose from abdominal CT examination using two different methods · 2026 · DOI
Most-cited papers in Radiation Dose and Imaging
- Computed Tomography — An Increasing Source of Radiation Exposure · New England Journal of Medicine · 2007 · 7,349 citations
- Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study · The Lancet · 2012 · 3,232 citations
- Radiation Dose Associated With Common Computed Tomography Examinations and the Associated Lifetime Attributable Risk of Cancer · Archives of Internal Medicine · 2009 · 2,071 citations
- Projected Cancer Risks From Computed Tomographic Scans Performed in the United States in 2007 · Archives of Internal Medicine · 2009 · 1,606 citations
- Risk of cancer from diagnostic X-rays: estimates for the UK and 14 other countries · The Lancet · 2004 · 1,363 citations
- Estimating Risk of Cancer Associated With Radiation Exposure From 64-Slice Computed Tomography Coronary Angiography · JAMA · 2007 · 1,180 citations
- Estimated Radiation Dose Associated With Cardiac CT Angiography · JAMA · 2009 · 855 citations
- Comparative dosimetry of dental CBCT devices and 64-slice CT for oral and maxillofacial radiology · Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology · 2008 · 664 citations
- Dosimetry of 3 CBCT devices for oral and maxillofacial radiology: CB Mercuray, NewTom 3G and i-CAT · Dentomaxillofacial Radiology · 2006 · 618 citations
- Radiation Risk to Children From Computed Tomography · PEDIATRICS · 2007 · 513 citations
Most recent work
- Generative AI-based low-dose digital subtraction angiography for intra-operative radiation dose reduction: a randomized controlled trial · Nature Medicine · 2026
- CT Radiation Dose Reduction With Preserved Diagnostic Performance: How Far Have We Come Over 25 Years? · American Journal of Roentgenology · 2026
- Recommendations From the Blue Ribbon Panel on Fluoroscopy Safety · Journal of the American College of Radiology · 2026
- Deep-learning image reconstruction algorithms for CT: A task-based image quality assessment of four CT systems using a phantom · Diagnostic and Interventional Imaging · 2026
- International survey in four European countries on diagnostic reference levels based on clinical indications in computed tomography · Insights into Imaging · 2026
- Occupational Protection in Interventional Radiology. A Joint Guideline of the Cardiovascular and Interventional Radiological Society of Europe and the Society of Interventional Radiology · CardioVascular and Interventional Radiology · 2026
- A step toward diagnostic reference levels for male varicocele embolization: dosimetric comparison across two generations of angiographic systems · La radiologia medica · 2026
- Survey of normalized CTDI vol values across four major computed tomography vendors for use in the MIRDct software · Journal of Applied Clinical Medical Physics · 2026
- Increasing Awareness and Reducing Occupational Hazards in the Cardiac Catheterization and Electrophysiology Laboratories · JACC Advances · 2026
- Factors Affecting Contrast Enhancement on CT Images · Radiographics · 2026
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