Science AI Journal
Medicine · Research topic

Open research questions in Ultrasound in Clinical Applications

148 unresolved questions extracted from the limitations and future-work sections of 526 Ultrasound in Clinical Applications papers in our library. Each links back to the study that raised it.

What the literature leaves open

  • The gap in current research is the lack of timely and precise identification of non-cardiac etiologies of chest pain, including pneumothorax, in pediatric emergency departments. The gap is addressed by evaluating the use of point-of-care lung ultrasound in a pediatric emergency department.

    Point-of-care lung ultrasound in the evaluation of chest pain in a pediatric emergency department · 2026 · DOI

  • inconsistent neonatal-specific thresholds, - operator dependence, - limited training infrastructure, - insufficient validation in extremely low birth weight populations

    From invasive to non-invasive: point-of-care ultrasound parameters and a clinical decision algorithm for central venous pressure assessment in critically Ill neonates · 2026 · DOI

  • The lack of standardized protocols for non-invasive CVP assessment in critically ill neonates using POCUS parameters. The need for dedicated neonatal training and credentialing standards for POCUS. The limited validation of POCUS parameters in extremely low birth weight populations.

    From invasive to non-invasive: point-of-care ultrasound parameters and a clinical decision algorithm for central venous pressure assessment in critically Ill neonates · 2026 · DOI

  • The review is based on a focused, non-systematic search of major databases. The underlying principles are clinically transferable but limited to adult ED literature. The proposed framework does not replace antimicrobials, source control, comprehensive imaging, or clinical judgment.

    Point-of-care ultrasound in emergency department sepsis and septic shock: a pragmatic framework for source-oriented assessment and physiologic reassessment · 2026 · DOI

  • Investigate the use of POCUS in pediatric populations. Explore the integration of POCUS with other diagnostic tools for improved accuracy.

    Point-of-care ultrasound in emergency department sepsis and septic shock: a pragmatic framework for source-oriented assessment and physiologic reassessment · 2026 · DOI

  • further studies are needed to investigate the use of point-of-care ultrasonography in pediatric emergency departments, - research on the long-term outcomes of patients with chest pain in pediatric emergency departments is needed, - studies on the cost-effectiveness of point-of-care ultrasonography in pediatric emergency departments could be conducted

    Point-of-care lung ultrasound in the evaluation of chest pain in a pediatric emergency department · 2026 · DOI

  • Lung ultrasound enables detection of extravascular lung water through B-lines, even in early stages, but its role in HFpEF patients managed in primary care remains poorly defined.

    Pulmonary congestion assessed by lung ultrasound in stable ambulatory patients with heart failure and preserved ejection fraction in primary care · 2026 · DOI

  • Overall, combined biomarker strategies and tools like lung ultrasound have shown promise in some studies, but current evidence is insufficient for broader clinical use.

    Research progress on biomarkers associated with neonatal respiratory distress syndrome · 2026 · DOI

  • Despite this, optimal training methods for CVS remain uncertain, particularly regarding whether techniques involving context variation, needle guides, or freehand approaches yield superior skill acquisition and performance.

    To guide or not to guide: A randomized study on the use of needle guide for chorionic villus sampling training · 2025 · DOI

  • Future research should focus on standardizing protocols and evaluating the impact of POCUS-guided management on patient outcomes.

    Point-of-care ultrasound in the evaluation of STEMI patients · 2025 · DOI

  • While current strategies incorporate digital learning and ultrasound simulators, the effectiveness of these simulators for learning remains uncertain.

    Simulator training in focus assessed transthoracic echocardiography (FATE) for undergraduate medical students: results from the FateSim randomized controlled trial · 2025 · DOI

  • BACKGROUND: Point-of-care ultrasound (POCUS) can be used in a variety of clinical settings and is a safe and powerful tool for ultrasound-trained healthcare providers, such as physicians and nurses; however, the effectiveness of ultrasound education for nursing students remains unclear.

    Sustained effects of bladder point-of-care ultrasound simulation exercise on nursing students: A prospective cohort study · 2025 · DOI

  • BACKGROUND: There exists no standardized longitudinal curriculum for teaching bedside ultrasonography (US) in Pulmonary and Critical Care Medicine (PCCM) fellowship programs.

    A longitudinal blended learning curriculum for bedside ultrasound education in pulmonary and critical care fellowship · 2025 · DOI

  • BACKGROUND: An educational gap for point-of-care-ultrasound (POCUS) training exists within Internal Medicine (IM) residency programs in that there is currently no standardized training paradigm.

    The design, performance and organizational impact of a point-of-care ultrasound (POCUS) elective for internal medicine residents · 2025 · DOI

  • However, evidence on the use of VExUS, particularly in combination with LUS, in critically ill children with fluid overload is scarce, and their clinical utility in this setting is yet to be established.

    Correlation between positive fluid balances with venous excess ultrasound scores and lung ultrasound in critically ill children with fluid overload · 2025 · DOI

  • Importance: The association of cardiopulmonary point-of-care ultrasonography (POCUS) with length of stay (LOS) and hospitalization costs for patients admitted to internal medicine wards remains uncertain.

    Cardiopulmonary Point-of-Care Ultrasonography for Hospitalist Management of Undifferentiated Dyspnea · 2025 · DOI

  • Introduction There have been few studies on predictors of weaning failure from MV in patients with heart failure (HF).

    B-lines by lung ultrasound as a predictor of re-intubation in mechanically ventilated patients with heart failure · 2024 · DOI

  • CONCLUSIONS: Despite a lack of consensus in POCUS education, existing literature describes many curricular designs across institutions.

    Development of a hybrid point-of-care ultrasound curriculum for first year medical students in a rural medical education program: a pilot study · 2024 · DOI

  • Integration of POCUS into paramedics' training curricula offers opportunities and should be further studied.

    Development and evaluation of a point-of-care ultrasound curriculum for paramedics in Germany – a prospective observational study and comparison · 2024 · DOI

  • CONTEXT: Point-of-Care Ultrasound (POCUS) has become an important tool in the clinical practice of many specialties, but its use and impact in General Practice in France remains to be explored.

    Consensus on relevant point-of-care ultrasound skills in General Practice: a two-round French Delphi study · 2024 · DOI

  • However, there are no data on the potential role of PoCUS in the preclinical training of medical students in Saudi Arabia.

    Investigating medical students’ perceptions of point-of-care ultrasound integration into preclinical education · 2024 · DOI

  • Common ultrasound usage barriers were insufficient scanning routine, supervision, knowledge, confidence and mental surplus.

    Ultrasound education, competencies and expected future use among medical interns in Denmark: a national cross-sectional study · 2024 · DOI

  • Such tools can potentially enhance ultrasound training, warranting the expansion of the application to more views and prompting further studies on long-term learning effects.

    The effect of real-time EF automatic tool on cardiac ultrasound performance among medical students · 2024 · DOI

  • However, the specific methodologies for utilizing LUS in clinical practice remain controversial.

    Prospective, non-blinded, randomized controlled trial on early administration of pulmonary surfactant guided by lung ultrasound scores in very preterm infants: study protocol · 2024 · DOI

  • The lung ultrasonography score (LUS) is accurate to guide surfactant replacement in early preterm neonates, but to our knowledge, it has not yet been studied in the late preterm through full-term neonatal population.

    Quantitative Lung Ultrasonography to Guide Surfactant Therapy in Neonates Born Late Preterm and Later · 2024 · DOI

Most-cited papers in Ultrasound in Clinical Applications

Most recent work

Find a gap in your own Ultrasound in Clinical Applications sub-topic

This page shows what the Ultrasound in Clinical Applications literature already flags as unresolved. To narrow it to your specific question, run the guided finder — it searches the gap library on demand and checks candidates against 250M+ OpenAlex works.

Open the Research Gap Finder →

Related topics in Medicine

Artificial Intelligence in Healthcare and Education
2,044 open questions
Substance Abuse Treatment and Outcomes
1,964 open questions
Smoking Behavior and Cessation
990 open questions
Dementia and Cognitive Impairment Research
974 open questions
Innovations in Medical Education
960 open questions
Physical Activity and Health
923 open questions
Attention Deficit Hyperactivity Disorder
839 open questions
Schizophrenia research and treatment
709 open questions
148 open questions have been extracted from the limitations and future-work passages of 526 Ultrasound in Clinical Applications papers in our library. Each one below links back to the study that raised it, so you can read the original claim in context.

Tools for your next paper

Gaps & Literature SearchFind open questions in any field — 120,000+ open gaps mined from our own library.Pre-CheckIs your paper ready? A Tier 1–5 acceptance probability in seconds.Journal FinderA ranked shortlist of target journals from a 17,500-venue index.Duplicate Publication CheckerCheck prior-publication & salami-slicing risk across 8 sources.Citation GeneratorFreeA DOI or title → APA, MLA, Vancouver, Chicago, BibTeX, RIS. No signup.Graphical Abstract MakerFreeTurn your findings into a colorblind-safe graphical abstract.

Compare the category — Honest roundups of the AI research tools, ours listed alongside the alternatives.

Command palette

Jump anywhere, run any action.