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Open research questions in Dental Trauma and Treatments

201 unresolved questions extracted from the limitations and future-work sections of 2,703 Dental Trauma and Treatments papers in our library. Each links back to the study that raised it.

What the literature leaves open

  • sample size is a minimum estimation and can be safely increased, - the study employed a double-blind design but the calculated sample size is a minimum estimation, - the methodology and clinical effectiveness of cryotherapy remain non-standardized

    Clinical and biochemical effects of cryotherapy protocols on mandibular premolars with symptomatic apical periodontitis: a randomized clinical trial · 2026 · DOI

  • Limited to patients treated at Niigata University Hospital, - Retrospective cohort study, - No additional follow-up visits were conducted beyond routine clinical care

    Long-term retention and prognostic factors in repaired vertically root-fractured teeth: A retrospective cohort study · 2026 · DOI

  • Investigation of long-term effects of root fracture repair on occlusal collapse, - Comparison of different adhesive resin cements for bonding-based repair, - Study of the impact of patient age and sex on retention outcomes

    Long-term retention and prognostic factors in repaired vertically root-fractured teeth: A retrospective cohort study · 2026 · DOI

  • investigation of the effects of different storage media on root resorption, - study of the impact of timing and type of endodontic treatment on root resorption

    Incidence and predictors of root resorption after delayed replantation of permanent teeth · 2026 · DOI

  • The long-term incidence and associated clinical factors of root resorption remain limited. There is a need to identify clinical factors associated with the occurrence of root resorption after delayed replantation of permanent teeth.

    Incidence and predictors of root resorption after delayed replantation of permanent teeth · 2026 · DOI

  • However, the influence of endodontic interventions, particularly apicoectomy, on outcomes of transplanting fully developed teeth remains incompletely understood.

    Assessing the impact of apicoectomy on autotransplantation success rates: A six-year retrospective cohort study in Taiwan · 2025 · DOI

  • Technical difficulty of applying direct reduction forces to the maxilla - Risk of hardware exposure and impaired soft tissue healing - Limited purchase of cortical bone in the midsagittal region

    Closed reduction of midline palatal fracture using a palatal acrylic splint and interdental wiring: case report · 2026 · DOI

  • There is a need for effective treatment options for midline palatal fractures, which can compromise transverse stability of the maxilla and lead to dental arch discrepancies and malocclusion. Current treatment options may not always provide optimal outcomes, highlighting the need for novel approaches.

    Closed reduction of midline palatal fracture using a palatal acrylic splint and interdental wiring: case report · 2026 · DOI

  • The need for effective treatment options for complicated crown–root fractures. The challenge of preserving the fractured root while ensuring aesthetic restorability.

    Management of a complicated crown root fractured tooth via intentional replantation with 180° rotation: a 4-year case report · 2026 · DOI

  • The success outcome is attributed substantially to patient compliance, oral hygiene protocols, and minimally invasive surgical procedures, yet the paper does not establish which specific surgical technique variables (e.g., replantation site preparation, socket conditioning, suture type, repositioning force) most critically influence healing outcomes in 180° rotation replantation.

    Management of a complicated crown root fractured tooth via intentional replantation with 180° rotation: a 4-year case report · 2026 · DOI

  • Gingival injury and inflammation are common complications of Erich arch bar placement. The use of antimicrobials, such as chlorhexidine and metronidazole, may not promote wound healing. There is a need for alternative treatments that can enhance gingival healing and regeneration.

    Comparative evaluation of the efficacy of human placental extract gel with metronidazole gel as a gingival wound healing agent following Erich arch bar placement: An in vivo study · 2026 · DOI

  • There is a lack of research on the efficacy of human placental extract gel as a gingival wound healing agent. There is a need for alternative treatments for gingival trauma that can enhance wound healing and regeneration.

    Comparative evaluation of the efficacy of human placental extract gel with metronidazole gel as a gingival wound healing agent following Erich arch bar placement: An in vivo study · 2026 · DOI

  • Further studies are needed to confirm the findings and evaluate the long-term outcomes of IOT. The study's results may be applicable to other dental procedures involving periodontal ligament vitality. Future research may investigate the underlying mechanisms of IOT in preserving periodontal ligament vitality.

    Ankylosis and external root resorption following intentional replantation using intermittent oxygenation technique: a Bayesian observational study · 2026 · DOI

  • Practical limitations such as cost and compliance challenges remain. The need for periodic replacement during active tooth movement is a barrier for adolescent patients. The paper does not provide a comprehensive solution to these challenges.

    Sports mouthguards and orthodontics: Current evidence and clinical perspectives - a narrative review · 2026 · DOI

  • There is a lack of compliance with mouthguard use among orthodontic patients. The need for periodic replacement during active tooth movement is a barrier for adolescent patients. There is a need for education on mouthguard use, fit, and replacement.

    Sports mouthguards and orthodontics: Current evidence and clinical perspectives - a narrative review · 2026 · DOI

  • There is a need for professional training in Primary Health Care to address dental trauma. There is a lack of awareness about the importance of treating dental trauma in children.

    TRAUMA DENTÁRIO NA INFÂNCIA E A IMPORTÂNCIA DA CAPACITAÇÃO DA EQUIPE DE SAÚDE BUCAL NA ESTRATÉGIA SAÚDE DA FAMÍLIA NO PARÁ: RELATO DE EXPERIÊNCIA · 2026 · DOI

  • There is a need for public education about traumatic dental injuries. There is a lack of awareness about the importance of mouthguards in preventing dental trauma.

    ‘Back of the net!' Developing new patient resources for dental trauma education · 2026 · DOI

  • The removal of additional tooth structure during post-core restoration can weaken the remaining root dentin. The high fracture rate of canine teeth requires effective restoration methods. The biomechanical effects of varying fiber post lengths are not well understood.

    Biomechanical Analysis of Post–Core Crown Restoration in Dog Maxillary Canine Teeth · 2026 · DOI

  • The study used a limited number of dog breeds. The study used a specific type of fiber post. The study did not evaluate the long-term effects of post-core restoration.

    Biomechanical Analysis of Post–Core Crown Restoration in Dog Maxillary Canine Teeth · 2026 · DOI

  • The paper is limited to a narrative literature review and does not include original research. The search was limited to articles published in Portuguese, English, and Spanish.

    Abordagem clínica das fraturas radiculares: uma revisão da literatura. · 2026 · DOI

  • The evidence regarding orthodontic treatment following regenerative endodontic therapy remains limited. Available studies are largely case reports, with low-quality evidence and a non-negligible incidence of adverse effects.

    Orthodontic treatment in immature teeth: A contemporary review of endodontic, periodontal, and biomechanical aspects · 2026 · DOI

  • The long-term consequences of orthodontic forces applied following regenerative endodontic therapy remain insufficiently evidenced. The biological effects of orthodontic movement on immature teeth are complex and less predictable in the presence of trauma or pulp necrosis.

    Orthodontic treatment in immature teeth: A contemporary review of endodontic, periodontal, and biomechanical aspects · 2026 · DOI

  • There is a need to evaluate the survival and complication rates of teeth restored with crowns following crown lengthening. The current study addresses this gap by assessing the restorability of teeth and the success of crowns in preventing further breakdown.

    Complications and Survival of Teeth Restored With Crowns Following Crown Lengthening: A Retrospective Cohort Study · 2026 · DOI

  • There is a need for effective treatment approaches for traumatic dental injuries in pregnant women. Conservative management is an alternative to tooth extraction and endodontic management.

    Conservative treatment of dental trauma for multiple teeth for a pregnant woman · 2026 · DOI

  • Postoperative edema is a significant complication after surgical extraction. Limited effective treatments for reducing postoperative edema. Variability in patient response to dexamethasone administration.

    Submucosal against Intramuscular Administration of Dexamethasone in Treatment of Postoperative Edema after Odontectomy of Impacted Mandibular Third Molars · 2026 · DOI

Most-cited papers in Dental Trauma and Treatments

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201 open questions have been extracted from the limitations and future-work passages of 2,703 Dental Trauma and Treatments papers in our library. Each one below links back to the study that raised it, so you can read the original claim in context.

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