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Open research questions in Nursing care and research

183 gap statements mined from Nursing care and research papers in our 7.9M-paper local library, which holds 1,012 papers on the topic — drawn mostly from each paper's own stated research gap, future-work, challenge and limitation notes, and its abstract. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one.

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What the literature leaves open

  • The study provides one of the first qualitative accounts of the experiences of family caregivers of people with colorectal cancer in Kazakhstan, offering insights from a Central Asian context where evidence on informal caregiving remains scarce.

    Caregiving Experiences, Supportive Care Needs and Coping Strategies Among Family Caregivers of Patients with Colorectal Cancer in Kazakhstan: A Qualitative Descriptive Study · 2026 · DOI

  • The analysis is limited by the use of claims data, which may not capture all relevant information. The study must account for the influence of sociodemographic and care-specific variables on relevant conditions.

    Morbidity patterns and mental health risks among informal caregivers: a diagnosis-based comparison with matched non-caregivers · 2026 · DOI

  • However, knowledge is still lacking among patients, relatives and healthcare professionals about how these symptoms affect the couple’s relationship, the experience of strain and quality of life.

    Exploring the Impact of Parkinson’s Disease on Marital Relationships · 2026 · DOI

  • Future research should consider using longitudinal or interventional designs to test these causal pathways, and should expand sample sizes and geographical scope to enhance the external validity of the results.

    Family resilience, dyadic coping, and health-related quality of life among primary caregivers of hospitalized older adults with multimorbidity in Xinjiang, China: a latent profile and mediation analysis · 2026 · DOI

  • Findings from this pragmatic evaluation study address a gap in the literature describing the impact of free-standing, low-barrier, telephonic, multi-touch programs designed to support family caregivers across the lifespan without regard to diagnosis or condition of the care recipient.

    Enhancing Family Caregiver Well-Being: Evaluation of Person-Centered Navigation Services · 2026 · DOI

  • Future research should focus on refining the social relationships domain and addressing minor fit inconsistencies to enhance the scale’s applicability further.

    Quality of Life Among Family Caregivers of Individuals With Rare Diseases: Web-Based Population Study on the Validity and Reliability of the Polish World Health Organization Quality of Life-BREF Questionnaire · 2025 · DOI

  • The limitations of this study include the sample containing only elderly people living at home since different stages of life can influence the way each person understands and responds to the items in the instrument, which could affect the factor structure.

    Translation, Adaptation, and Validation of the Portuguese Version of the Exercise of Self-Care Agency Scale · 2024 · DOI

  • Larger methodologically rigorous studies are warranted to confirm this emerging evidence.

    Effectiveness of interventions for caregiver burden and quality of life of informal caregivers of stroke survivors: a systematic review and meta-analysis · 2026 · DOI

  • These findings suggest that restorative free time may warrant further investigation as a potential for future intervention research.

    Restorative free time and psychological distress among employed family caregivers of individuals with cognitive impairment: a cross-sectional study · 2026 · DOI

  • Yet, how couple-level interactions shape outcomes—or how nurses can harness dyadic resources in care—remains poorly understood.

    Coping and Resilience in Chinese Couples with Connective Tissue Diseases: A Culturally Informed Qualitative Explanation · 2026 · DOI

  • By promoting shared appraisals and open communication in a dyadic approach, the novel counselling method addresses a largely underexplored area.

    Collaborative Care and Everyday Planning in Care Counselling (CoPlan study): study protocol of a pragmatic randomized clinical trial and protocol changes to quasi-experimental evaluation during recruitment · 2026 · DOI

  • These findings indicate that interventions aimed at reducing caregiver burden and addressing caregiver support needs warrant further investigation.

    Impact of Caregiver Burden and Care Recipients′ Activities of Daily Living Abilities on Caregivers′ Occupational Dysfunction · 2026 · DOI

  • Informal caregivers support patient self-care, but the mechanisms underlying variability in caregiver contribution (CC) are not fully understood.

    Caregiver Self-Efficacy as a Mediator of Caregiver Contribution to Self-Care in Coronary Heart Disease: A Cross-Sectional Structural Equation Modeling Study · 2026 · DOI

  • Women informal caregivers are overrepresented in unpaid and informal caregiving roles yet remain underrecognized as patients and policy subjects within health and social care systems.

    Invisible patients: Reframing women informal caregivers’ access to healthcare and support services as a gendered health systems issue · 2026 · DOI

  • However, no studies have confirmed that the combined support of internal individual factors and external family environmental factors may play an important role in the self-management of patients with early CKD.

    Family Function and Self-Management of Patients With Early Chronic Kidney Disease: The Mediating Roles of Self-Perceived Burden and Ego Depletion · 2025 · DOI

  • Despite their vital contributions and growing policy initiatives, ICs' involvement in hospital discharge planning remains insufficiently recognized.

    Informal Caregivers in Transitional Hospital-to-Home Care for Older People: Addressing Gaps in Pre-Discharge Collaboration for Enhanced Patient Outcomes · 2025 · DOI

  • However, its suitability for the Taiwanese healthcare context has not yet been established.

    Translation, Adaptation, and Validation of a Traditional Chinese Version of the Family Caregiver Medication Administration Hassle Scale · 2025 · DOI

  • Future research should explore social and demographic determinants of medication-related caregiving stress and develop targeted interventions to support caregivers in Taiwan.

    Translation, Adaptation, and Validation of a Traditional Chinese Version of the Family Caregiver Medication Administration Hassle Scale · 2025 · DOI

  • Further research on the results of these findings is needed on how caregivers maintain their quality of life as they begin to become caregivers.

    Devotion to Family: Coping Strategy to Reduce Burden of Caregiving Stroke Patients · 2025 · DOI

  • However, it remains unclear how family caregivers experiencing financial strain adapt to both caregiving and daily life.

    Impact of Financial Burden on Family Caregivers of Older Adults Using Long-Term Care Insurance Services · 2025 · DOI

  • The degree of congruence between patients' and caregivers' perceptions of chronic illness should be explored to gain a holistic understanding of the dyadic illness management.

    Profiles of Dyadic Self-care Congruence and Patient Symptom Burden in Heart Failure · 2025 · DOI

  • Although caregiver burden is recognized in other chronic conditions, little is known about burden, health-related quality of life (HRQoL), and engagement among caregivers of patients with AF across Europe.

    Informal Caregiving in Patients With Atrial Fibrillation and Multimorbidity: A Cross-European Study of Caregiver Burden, Health-Related Quality of Life, and Caregiver Engagement · 2025 · DOI

  • Caregiver coping strategies to reduce this burden have not been widely studied, especially in Indonesia.

    Devotion to Family: Coping Strategy to Reduce Burden of Caregiving Stroke Patients · 2025 · DOI

  • Intergenerational support, an important component of family resilience for older patients, has been mentioned by some researchers but not fully explored…

    Family resilience for older patients requiring long-term care: a concept analysis · 2026 · DOI

  • Critical appraisal of definitions indicated inadequately defined aspects such as setting, temporal dimension, concept interaction, interventions, and measurable outcomes.

    Defining Self-Management for Solid Organ Transplantation Recipients: A Mixed Method Study · 2024 · DOI

Most-cited papers in Nursing care and research

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Open questions raised by papers listed on this page include: (1) Knowledge is still lacking among patients, relatives and healthcare professionals about how these symptoms affect the couple’s relationship, the experience of strain and quality of life (“Exploring the Impact of Parkinson’s Disease on Marital Relationships”, 2026); (2) Future research should consider using longitudinal or interventional designs to test these causal pathways, and should expand sample sizes and geographical scope to enhance the external validity of the results (“Family resilience, dyadic coping, and health-related quality of life among…”, 2026); (3) Larger methodologically rigorous studies are warranted to confirm this emerging evidence (“Effectiveness of interventions for caregiver burden and quality of life of…”, 2026); (4) How couple-level interactions shape outcomes—or how nurses can harness dyadic resources in care—remains poorly understood (“Coping and Resilience in Chinese Couples with Connective Tissue Diseases: A…”, 2026); (5) Informal caregivers support patient self-care, but the mechanisms underlying variability in caregiver contribution (CC) are not fully understood (“Caregiver Self-Efficacy as a Mediator of Caregiver Contribution to Self-Care in…”, 2026). 183 gap statements have been mined from Nursing care and research papers in our 7.9M-paper local library, which holds 1,012 papers on the topic; the gaps come from whichever of those papers state one. They are mostly the research gaps the authors state and the papers' abstracts, plus future-work, limitations and challenges passages. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one, so you can read the original claim in context.

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