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Pharmacology, Toxicology and Pharmaceutics · Research topic

Open research questions in Pharmacology and Nanomedicine Research

53 unresolved questions extracted from the limitations and future-work sections of 102 Pharmacology and Nanomedicine Research papers in our library. Each links back to the study that raised it.

What the literature leaves open

  • Inflammation and degeneration of the gums, supporting bone, periodontal ligament, and cementum. Change in the microflora, shifting from a Gram-positive anaerobic flora to a more Gram-negative one. Limited effectiveness of current treatments for periodontal disease.

    RESEARCH ON FORMULATION & EVALUATION OF "DENTAL GEL CONTAINING CLOVE OIL FOR THE TREATMENT OF PERIODENTAL DISEASE · 2026 · DOI

  • The increasing prevalence of mental disorders. The need for a holistic approach to preserve mental health. The importance of addressing spiritual and social factors in mental health.

    ROLE OF SWASTHAVRITTA AS AYURVEDIC REMEDIES IN MENTAL AND BEHAVIORAL DISORDER · 2026 · DOI

  • High toxicity, limited selectivity, and the development of drug resistance associated with conventional chemotherapeutic agents. The need to explore alternative sources for anticancer drug discovery.

    Cytotoxic Evaluation of Medicinal Plants used by Suku Anak Dalam Community in Jambi Province Using the Brine Shrimp Lethality Test · 2026 · DOI

  • Further evaluation of the polyherbal mouthwash for its clinical efficacy. Investigation of the formulation's stability and shelf-life. Development of new polyherbal mouthwash formulations with improved characteristics.

    Formulation and Evaluation of Polyherbal Mouthwash Using Neem And Tulsi · 2026 · DOI

  • The emergence of antimicrobial resistance. The need to develop alternative antimicrobial agents.

    COMPARATIVE EVALUATION OF ANTIMICROBIAL ACTIVITY OF SURYAPAKI KUSHTHARAKSHASA TAILA PREPARED WITH WATER AND WITHOUT WATER BY WELL DIFFUSION METHOD · 2026 · DOI

  • The need for alternative mouthwash formulations. The potential of polyherbal mouthwashes in maintaining oral hygiene.

    Formulation and Evaluation of Polyherbal Mouthwash Using Neem And Tulsi · 2026 · DOI

  • The optimised formulation has the potential to be a biodegradable Ayurvedic shampoo and should be further investigated through clinical evaluation, safety evaluations, and stability investigations.

    FORMULATION AND EVALUATION OF A POLYHERBAL SHAMPOO INCORPORATING SEVEN AYURVEDIC BOTANICAL EXTRACTS · 2026 · DOI

  • Long-term follow-up studies are needed to assess the sustainability of the effects of education and consultation. Studies should investigate the effectiveness of different educational interventions in improving patient knowledge and adherence.

    Peningkatan Pengetahuan Efek Samping Obat Antidiabetes melalui Edukasi pada Pasien Diabetes Mellitus di Kelurahan Angke, Jakarta Barat · 2026 · DOI

  • Limited understanding of antidiabetic drug side effects contributes to non-adherence. There is a need for effective interventions to improve patient knowledge and adherence.

    Peningkatan Pengetahuan Efek Samping Obat Antidiabetes melalui Edukasi pada Pasien Diabetes Mellitus di Kelurahan Angke, Jakarta Barat · 2026 · DOI

  • There is a need for effective and convenient approaches for the management of rheumatoid arthritis. Conventional management mainly includes non-steroidal anti-inflammatory drugs (NSAIDs) which may result in adverse effects.

    Formulation and Evaluation of Pain Relief Roll-On Containing Diclofenac Sodium and Curcumin for Rheumatoid Arthritis · 2026 · DOI

  • There is a need for the development of herbal products for the treatment of periodontal disease. The current treatments for periodontal disease have limitations and side effects.

    RESEARCH ON FORMULATION & EVALUATION OF "DENTAL GEL CONTAINING CLOVE OIL FOR THE TREATMENT OF PERIODENTAL DISEASE · 2026 · DOI

  • Further studies using advanced analytical techniques are needed to fully characterize the formulation. The use of other spectroscopic techniques, such as NMR or MS, may provide additional information.

    ASSESSMENT OF FUNCTIONAL GROUPS IN MARUTHAM PATTAI KUDINEER USING FOURIER TRANSFORM INFRARED (FTIR) SPECTROSCOPY · 2026 · DOI

  • Further research can be done on the effectiveness of Ayurvedic techniques in treating mental disorders. The role of spiritual and social activities in mental health can be explored further.

    ROLE OF SWASTHAVRITTA AS AYURVEDIC REMEDIES IN MENTAL AND BEHAVIORAL DISORDER · 2026 · DOI

  • Conventional treatments for burns and burn scars have side effects and limited efficacy. There is a need for a safe and effective natural alternative.

    Formulation and Evaluation of Herbal Cream of Terminalia Arjuna Bark for Burn Spot Removal · 2026 · DOI

  • The search for effective, affordable, and safer anticancer agents continues to be a global priority. There is a need to explore alternative sources for anticancer drug discovery.

    Cytotoxic Evaluation of Medicinal Plants used by Suku Anak Dalam Community in Jambi Province Using the Brine Shrimp Lethality Test · 2026 · DOI

  • The modern literature for direct ocular pharmacology of these oils is developing. There is a need for defined specifications and validated methods for physico-chemical testing.

    Review on the Pharmaceutical and Cosmetic Significance of Castor Oil, Almond Oil, and Ghee in Vedic Kajal · 2026 · DOI

  • The emergence of antimicrobial resistance has encouraged the scientific evaluation of traditional Ayurvedic formulations. There is a need to evaluate the antimicrobial activity of Ayurvedic formulations.

    COMPARATIVE EVALUATION OF ANTIMICROBIAL ACTIVITY OF SURYAPAKI KUSHTHARAKSHASA TAILA PREPARED WITH WATER AND WITHOUT WATER BY WELL DIFFUSION METHOD · 2026 · DOI

  • The need for a natural and effective topical formulation for managing common periocular concerns. The lack of a stable, safe, and effective herbal under-eye gel in the market.

    FORMULATION AND EVALUATION OF HERBAL UNDER-EYE GEL USING CUCUMBER AND POTATO EXTRACTS · 2026 · DOI

  • The lack of safer and more effective alternatives to conventional oral medications for sleep induction. The need for herbal medicines that can provide rapid onset of action and improved therapeutic efficacy.

    FORMULATION AND EVALUATION OF POLYHERBAL ORAL THIN FILM FOR SLEEP INDUCTION · 2026 · DOI

  • Conventional face wash formulations often contain synthetic surfactants and preservatives. There is a need for innovative, eco-friendly, and sustainable cosmetic dosage forms.

    TO DESIGN AND CHARACTERIZATION OF NOVEL HERBAL FACE WASH TABLET INCORPORATING NELUMBO NUCIFERA (LOTUS), CHRYSOPOGON ZIZANIOIDES (VETIVER GRASS) AND MORINGA OLEIFERA · 2026 · DOI

  • The development of new extraction technologies and nanotechnology for herbal cosmetics. The study of the efficacy and safety of herbal cosmetics. The promotion of natural and eco-friendly lifestyles through the use of herbal cosmetics.

    A REVIEW ON HERBAL COSMETICS: FROM TRADITIONAL ROOTS TO MODERN INNOVATIONS · 2026 · DOI

  • Further scientific validation is still needed. The paper does not provide any clinical trials or experimental results to support the effectiveness of Anjanam.

    EXPLORING THE ROLE OF ANJANAM (COLLYRIUM) IN SIDDHA MEDICINE FOR EYE DISEASES · 2026 · DOI

  • There is a lack of scientific validation for the effectiveness of Anjanam. There is a need for further research on the mechanism of action of Anjanam.

    EXPLORING THE ROLE OF ANJANAM (COLLYRIUM) IN SIDDHA MEDICINE FOR EYE DISEASES · 2026 · DOI

  • Further studies on the standardization of herbal creams using modern scientific tools. Investigation of the therapeutic and cosmetic applications of herbal cream formulations. Development of new analytical techniques for quality control and scientific validation of herbal products.

    STANDARDIZATION OF HERBAL DRUGS WITH SPECIAL EMPHASIS ON HERBAL CREAM: A REVIEW RESEARCH ARTICLE · 2026 · DOI

  • Lack of standardization in herbal drugs. Variability in phytochemical constituents and lack of standard manufacturing procedures. Need for quality control and scientific validation of herbal products.

    STANDARDIZATION OF HERBAL DRUGS WITH SPECIAL EMPHASIS ON HERBAL CREAM: A REVIEW RESEARCH ARTICLE · 2026 · DOI

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53 open questions have been extracted from the limitations and future-work passages of 102 Pharmacology and Nanomedicine Research papers in our library. Each one below links back to the study that raised it, so you can read the original claim in context.

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