Science AI Journal
Pharmacology, Toxicology and Pharmaceutics · Research topic

Open research questions in Pharmacology and Nanomedicine Research

63 gap statements mined from Pharmacology and Nanomedicine Research papers in our 4.5M-paper local library, which holds 133 papers on the topic — drawn mostly from each paper's own stated research gap, future-work, challenge and limitation notes, and its abstract. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one.

Choosing where to publish on Pharmacology and Nanomedicine Research? See the ranked Medicine journals.

What the literature leaves open

  • There is a need to further study the pharmacological activities of Tagetes erecta. The plant's chemical constituents and their potential as a source of new drugs require further research.

    PHARMACOLOGICAL POTENTIAL OF TAGETES ERECTA: A REVIEW · 2026 · DOI

  • Future research can focus on the development of herbal formulations using Bryophyllum pinnatum. Future research can investigate the pharmacological action of Bryophyllum pinnatum.

    A Review on Formulation and Evaluation of Poly Herbal Syrup · 2026 · DOI

  • There is a need to review the formulation and evaluation of poly herbal syrup. There is a need to highlight the therapeutic potential of Bryophyllum pinnatum.

    A Review on Formulation and Evaluation of Poly Herbal Syrup · 2026 · DOI

  • There is a need to study the effectiveness of Siddha treatment in healing Chronic Varicose Ulcer. There is a lack of research on the use of Maththan Thailam in treating Chronic Varicose Ulcer.

    EFFECTIVE MANAGEMENT OF CHRONIC VARICOSE ULCER THROUGH SIDDHA TREATMENT - A CASE STUDY · 2026 · DOI

  • Long-term follow-up studies are needed to assess the sustainability of the effects of education and consultation. Studies should investigate the effectiveness of different educational interventions in improving patient knowledge and adherence.

    Peningkatan Pengetahuan Efek Samping Obat Antidiabetes melalui Edukasi pada Pasien Diabetes Mellitus di Kelurahan Angke, Jakarta Barat · 2026 · DOI

  • There is a need for the development of herbal products for the treatment of periodontal disease. The current treatments for periodontal disease have limitations and side effects.

    RESEARCH ON FORMULATION & EVALUATION OF "DENTAL GEL CONTAINING CLOVE OIL FOR THE TREATMENT OF PERIODENTAL DISEASE · 2026 · DOI

  • Further studies using advanced analytical techniques are needed to fully characterize the formulation. The use of other spectroscopic techniques, such as NMR or MS, may provide additional information.

    ASSESSMENT OF FUNCTIONAL GROUPS IN MARUTHAM PATTAI KUDINEER USING FOURIER TRANSFORM INFRARED (FTIR) SPECTROSCOPY · 2026 · DOI

  • Further research can be done on the effectiveness of Ayurvedic techniques in treating mental disorders. The role of spiritual and social activities in mental health can be explored further.

    ROLE OF SWASTHAVRITTA AS AYURVEDIC REMEDIES IN MENTAL AND BEHAVIORAL DISORDER · 2026 · DOI

  • High toxicity, limited selectivity, and the development of drug resistance associated with conventional chemotherapeutic agents. The need to explore alternative sources for anticancer drug discovery.

    Cytotoxic Evaluation of Medicinal Plants used by Suku Anak Dalam Community in Jambi Province Using the Brine Shrimp Lethality Test · 2026 · DOI

  • The search for effective, affordable, and safer anticancer agents continues to be a global priority. There is a need to explore alternative sources for anticancer drug discovery.

    Cytotoxic Evaluation of Medicinal Plants used by Suku Anak Dalam Community in Jambi Province Using the Brine Shrimp Lethality Test · 2026 · DOI

  • The emergence of antimicrobial resistance has encouraged the scientific evaluation of traditional Ayurvedic formulations. There is a need to evaluate the antimicrobial activity of Ayurvedic formulations.

    COMPARATIVE EVALUATION OF ANTIMICROBIAL ACTIVITY OF SURYAPAKI KUSHTHARAKSHASA TAILA PREPARED WITH WATER AND WITHOUT WATER BY WELL DIFFUSION METHOD · 2026 · DOI

  • The need for a natural and effective topical formulation for managing common periocular concerns. The lack of a stable, safe, and effective herbal under-eye gel in the market.

    FORMULATION AND EVALUATION OF HERBAL UNDER-EYE GEL USING CUCUMBER AND POTATO EXTRACTS · 2026 · DOI

  • The lack of safer and more effective alternatives to conventional oral medications for sleep induction. The need for herbal medicines that can provide rapid onset of action and improved therapeutic efficacy.

    FORMULATION AND EVALUATION OF POLYHERBAL ORAL THIN FILM FOR SLEEP INDUCTION · 2026 · DOI

  • Further scientific validation is still needed. The paper does not provide any clinical trials or experimental results to support the effectiveness of Anjanam.

    EXPLORING THE ROLE OF ANJANAM (COLLYRIUM) IN SIDDHA MEDICINE FOR EYE DISEASES · 2026 · DOI

  • There is a lack of scientific validation for the effectiveness of Anjanam. There is a need for further research on the mechanism of action of Anjanam.

    EXPLORING THE ROLE OF ANJANAM (COLLYRIUM) IN SIDDHA MEDICINE FOR EYE DISEASES · 2026 · DOI

  • There is a growing demand for natural products and natural extracts in cosmetics preparations. The paper identifies a need for a hand warming cream that provides a warming effect on the skin.

    PREPARATION AND EVALUATION OF HAND WARMING CREAM · 2026 · DOI

  • There is a need for further clinical investigations to establish the efficacy and safety of T. rhomboidea in humans. There is a lack of information on the plant's toxicological profile.

    TRIUMFETTA RHOMBOIDEA JACQ.: A COMPREHENSIVE REVIEW OF ITS ETHNOPHARMACOLOGY, PHYTOCHEMISTRY, AND THERAPEUTIC POTENTIAL · 2026 · DOI

  • The need for safer, natural, and non-invasive alternatives for managing menstrual pain. The lack of effective topical formulations for relieving menstrual pain.

    FORMULATION AND EVALUATION OF MENSTRUAL PAIN RELIEF ROLL-ON · 2026 · DOI

  • The formulation has limitations such as shorter shelf life and lower water resistance. The use of natural ingredients can lead to faster color fading. The formulation may need reapplication during the day.

    HERBAL BLUSH FORMULATION: A SAFE AND SKIN - FRIENDLY APPROACH · 2026 · DOI

  • Future research can focus on improving the shelf life and water resistance of the formulation. Further research can be done on using other natural ingredients as pigments.

    HERBAL BLUSH FORMULATION: A SAFE AND SKIN - FRIENDLY APPROACH · 2026 · DOI

  • Limited effectiveness of current treatments for periodontal disease.

    RESEARCH ON FORMULATION & EVALUATION OF "DENTAL GEL CONTAINING CLOVE OIL FOR THE TREATMENT OF PERIODENTAL DISEASE · 2026 · DOI

  • Further antimicrobial studies can be carried out against different UTI-causing microorganisms such as Escherichia coli, Klebsiella pneumoniae, and Proteus species. 2) Advanced Phytochemical Analysis: Advanced phytochemical analysis and isolation of active constituents from Corn Silk can be performed for a better understanding of its therapeutic activity.

    FORMULATION AND EVALUATION OF CORN SILK (STIGMA MAYDIS) HERBAL SYRUP FOR THE SUPPORTIVE MANAGEMENT OF URINARY TRACT INFECTIONS · 2026 · DOI

  • The development of new extraction technologies and nanotechnology for herbal cosmetics. The study of the efficacy and safety of herbal cosmetics. The promotion of natural and eco-friendly lifestyles through the use of herbal cosmetics.

    A REVIEW ON HERBAL COSMETICS: FROM TRADITIONAL ROOTS TO MODERN INNOVATIONS · 2026 · DOI

  • Evaluate the cream on different skin types for hydration, relaxation, and skin repair effects. Advanced Formulations: Develop nanoemulsion and gel-based systems for better absorption of essential oils. Product Diversification: Introduce related products such as night serum, body lotion, and under-eye gel.

    FORMULATION AND EVALUATION OF HERBAL CREAM FOR SUPPORTING SKIN HEALTH AND CIRCADIAN BALANCE · 2026 · DOI

  • Penelitian sebelumnya belum membahas tentang interaksi obat antihipertensi pada pasien GGK. Penelitian ini dapat membantu mengisi kesenjangan pengetahuan tentang interaksi obat antihipertensi pada pasien GGK.

    Analisis Interaksi Obat Antihipertensi Pada Pasien Gagal Ginjal Kronik di RSUD Dr. R. Sosodoro Djatikoesoemo · 2026 · DOI

Most-cited papers in Pharmacology and Nanomedicine Research

Most recent work

Find a gap in your own Pharmacology and Nanomedicine Research sub-topic

This page shows what the Pharmacology and Nanomedicine Research literature already flags as unresolved. To narrow it to your specific question, search the Research Gap Finder: the search is free with a free account and lists the papers closest to your topic first. Unlocking that topic (50 credits, charged once) fills the comparison table from our 4.5M-paper local library and writes the gaps from its rows.

Open the Research Gap Finder →

Related topics in Pharmacology, Toxicology and Pharmaceutics

Forensic Toxicology and Drug Analysis
281 open questions
Pharmacovigilance and Adverse Drug Reactions
240 open questions
Advancements in Transdermal Drug Delivery
225 open questions
Drug Solubulity and Delivery Systems
199 open questions
Drug-Induced Hepatotoxicity and Protection
183 open questions
Pharmacogenetics and Drug Metabolism
167 open questions
Advanced Drug Delivery Systems
135 open questions
Open questions raised by papers listed on this page include: (1) There is a need to further study the pharmacological activities of Tagetes erecta (“PHARMACOLOGICAL POTENTIAL OF TAGETES ERECTA: A REVIEW”, 2026); (2) Future research can focus on the development of herbal formulations using Bryophyllum pinnatum (“A Review on Formulation and Evaluation of Poly Herbal Syrup”, 2026); (3) There is a need to study the effectiveness of Siddha treatment in healing Chronic Varicose Ulcer (“EFFECTIVE MANAGEMENT OF CHRONIC VARICOSE ULCER THROUGH SIDDHA TREATMENT - A…”, 2026); (4) Long-term follow-up studies are needed to assess the sustainability of the effects of education and consultation (“Peningkatan Pengetahuan Efek Samping Obat Antidiabetes melalui Edukasi pada…”, 2026); (5) There is a need for the development of herbal products for the treatment of periodontal disease (“RESEARCH ON FORMULATION & EVALUATION OF "DENTAL GEL CONTAINING CLOVE OIL FOR…”, 2026). 63 gap statements have been mined from Pharmacology and Nanomedicine Research papers in our 4.5M-paper local library, which holds 133 papers on the topic; the gaps come from whichever of those papers state one. They are mostly the research gaps the authors state and the papers' abstracts, plus future-work, limitations and challenges passages. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one, so you can read the original claim in context.

Tools for your next paper

Gaps & Literature SearchFind open questions in any field — 120,000+ open gaps mined from our own library.Pre-CheckIs your paper ready? Acceptance odds for top, mid and open/emerging journals, in seconds.Journal FinderA ranked shortlist of target journals from a 17,500-venue index.Duplicate Publication CheckerCheck for prior publication across 7 sources and our local library.Citation GeneratorFreeA DOI or title → APA, MLA, Vancouver, Chicago, BibTeX, RIS. No signup.Graphical Abstract MakerFreeTurn your findings into a colorblind-safe graphical abstract.

How Pre-Check worksHow AI Review works

Compare the category — Honest roundups of the AI research tools, ours listed alongside the alternatives.

Command palette

Jump anywhere, run any action.