Open research questions in Various Chemistry Research Topics
213 gap statements mined from Various Chemistry Research Topics papers in our 7.9M-paper local library, which holds 2,239 papers on the topic — drawn mostly from each paper's own stated research gap, future-work, challenge and limitation notes, and its abstract. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one.
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What the literature leaves open
Understanding liquid surface tension and capillary action is vital for the study of fundamental chemical theories and advanced technologies, but these studies are still insufficient.
Revealing the Diffusion Coffee Ring on Hydrophilic Paper for Popular Science Learning of Liquid Surface Tension and Capillary Action in Microchannels · 2026 · DOITraditional titration or gas-volumetric methods are laborious, require substantial reagents, and often yield inconsistent results.
Upgrading Smartphone RGB Colorimetry for Rapid Determination of Hydrogen Peroxide Decomposition Kinetics · 2026 · DOIWhile molecular models incorporating magnets to simulate hydrogen bonding have been previously introduced, their potential as effective educational tools has not been fully explored.
WaterPuzzle: An Educational Activity Using a 3D-Printable Magnetic Molecular Model to Explore Hydrogen Bonding, Ice Crystals, and Hydration of Molecules · 2026 · DOIDespite their relevance, these skills are insufficiently addressed in everyday school teaching.
Codesigning Learning for the Future: Participatory Development of a Student Laboratory to Promote Transversal Skills · 2025 · DOIWhile every relevant textbook has quality figures to aid students in grasping the underlying theory, gaps in understanding the connection between mathematical functions and orbital diagrams may be partially corrected by improved instructional tools.
An R Shiny Application for Visualizing the Radial Distribution Functions of Hydrogen-Like Atoms · 2025 · DOIHowever, their impact on upper division chemistry laboratories has not been investigated.
Prelab Simulation of Microscope Building Activity in Upper Division Laboratory Improves Student Confidence · 2025 · DOIStudents were excited by the analysis of the large data set from the Internet in comparison to traditional limited data in textbooks and appreciated their acquired knowledge about bonding patterns.
Although undergraduate teaching effectively conveys the methodology, the rationale behind the inclusion of the constant “2” in the formula is rarely discussed and remains unclear.
Exploring the Impact of Dissolved Organic Matter on Nitrate Detection: Developing a Lab Experiment Using Standard Ultraviolet Spectrophotometry · 2024 · DOIHowever, little is known about employers’ expectations for specific instrument knowledge as chemistry students enter industry.
Survey of Instrumentation Use in Industry: What Does Industry Want New Chemists to Know? · 2024 · DOIWhile it is widely accepted that there should be equal access to education regardless of disability status, the chemistry laboratory tends to be an area where equal access is lacking for blind and visually impaired (BVI) students.
Modifying an Organic Chemistry Esterification Teaching Lab to Be Accessible to Blind and Visually Impaired (BVI) Students · 2024 · DOIWhile these reactions are typically covered in separate experiments in undergraduate organic courses, a continuous experimental setup elucidating both S E Ar and S N Ar processes remains unexplored in the literature for undergraduate laboratories.
Two-Step Synthesis of 4-Hydroxy-3,5-dimethylphenyl Benzoate: Undergraduate Organic Laboratory of Electrophilic Aromatic Substitution and Nucleophilic Aromatic Substitution · 2024 · DOICompared with flat sheet membranes, which have been frequently applied for EIS measurements, the characterization and analysis of hollow fiber membranes through EIS remain an underexplored area, offering a trove of possibilities for innovative research.
Exploring Electrochemistry: A Self-Designed Experiment by Students for Electrochemical Impedance Spectroscopy Measurement of Hollow Fiber Membranes · 2024 · DOIIncorporation of CDC and its characterization techniques, such as 1 H NMR and mass spectrometry (MS), into chemistry education is warranted to support CDC-relevant learning experiences, understanding of spectroscopy instrumentation, and student motivation to pursue a professional career.
Orthogonal Linking of Gemcitabine by Acyclovir and Bortezomib: A Rational Chemistry Laboratory Introduction of Both Noncovalent and Covalent Dynamics · 2024 · DOILimited access to advanced analytical instrumentation. Intimidation and lack of confidence among students when encountering advanced instrumentation for the first time.
A Study on Student Perceptions and Engagement With a Virtual Instrumentation Twin in an Undergraduate Analytical Chemistry Laboratory · 2026 · DOIThe lack of a conceptual bridge between quantum concepts and organic mechanisms.
Introducing a simplified model of frontier molecular orbital theory as a pre-organic foundations module for high school students in advanced programs · 2026 · DOICopper is a common material for drinking water service lines, and exposure to elevated levels of copper due to the corrosion of copper pipes causes harmful health effects, but few studies have focused on drinking water copper in underserved communities.
General Education Classroom Activity To Monitor Copper in Drinking Water: Civic Engagement in Environmental Justice Issues · 2026 · DOIEnvironmental pollutants such as per- and polyfluoroalkyl substances (PFAS) and microplastics (MPs) are urgent yet poorly understood risks demanding new approaches to public engagement.
Interdisciplinary Pedagogy for Environmental Chemistry Communication through Art–Engineering Collaboration · 2026 · DOIPractical experience with modern analytical instruments is an essential component of undergraduate chemistry education, yet access to advanced instruments varies widely among institutions because of differences in available resources.
A Guided Size Exclusion Chromatography Demonstration for Teaching Polymer Separation and Characterization · 2026 · DOIDespite its advantages, its integration into educational settings has been limited to a select few institutions.
Improved Continuous Flow Synthesis of a Diazo Dye in a Teaching Laboratory and Its Digitalization · 2025 · DOIThe concept of using appropriate statistical methods to compare results from a newly proposed analytical method to a standard method can be poorly understood among undergraduate students.
Comparison of qNMR Spectroscopy and an Enzyme-Based Standard Method for the Determination of Ethanol in Nonalcoholic Beer · 2025 · DOIThis review argues that this transformation is not the result of isolated improvements, but the synergistic convergence of three interconnected developments.
Transforming the Undergraduate Photochemistry Lab: A Convergence of Tools, Sustainability and Pedagogy · 2026 · DOIThis study suggests that in a country with a broad-based second-level education system prior experience of chemistry amongst students transitioning to university differs substantially, and that even for those who have taken the subject at senior cycle, the patterns of participation in practical chemistry varied widely.
From varied school science backgrounds to university: student expectations and perceptions of a UDL-aligned chemistry practical course · 2026 · DOIMore importantly, it bridges the educational gap in understanding advanced catalytic mechanisms and techniques in organic chemistry.
Integrating Bifunctional Catalysis into Senior Undergraduate Organic Chemistry: A Laboratory Experiment on the Asymmetric Michael Addition Reaction · 2024 · DOIThe limitations of traditional Natural Medicinal Chemistry experiment courses, - The need for a systematic understanding of the material basis of natural…
Constructing a Dynamic Material Perspective of Natural Medicines through Inquiry-Based Experiments: A Case Study of Analyzing Pre- and Post-Processing Components of Panax ginseng and Panax quinquefolius by UPLC · 2026 · DOIFurther investigation of the effectiveness of virtual reality as a learning tool in analytical chemistry education. Exploration of the potential of virtual reality to enhance students' learning experiences in other areas of chemistry.
A Study on Student Perceptions and Engagement With a Virtual Instrumentation Twin in an Undergraduate Analytical Chemistry Laboratory · 2026 · DOI
Most-cited papers in Various Chemistry Research Topics
- A Graphical Journey of Innovative Organic Architectures That Have Improved Our Lives · Journal of Chemical Education · 2010 · 1,134 citations
- ChemSpider: An Online Chemical Information Resource · Journal of Chemical Education · 2010 · 1,047 citations
- CREST—A program for the exploration of low-energy molecular chemical space · The Journal of Chemical Physics · 2024 · 448 citations
- The Henderson-Hasselbalch Equation: Its History and Limitations · Journal of Chemical Education · 2001 · 440 citations
- Macro, Submicro, and Symbolic: The many faces of the chemistry “triplet” · International Journal of Science Education · 2010 · 399 citations
- Improving Teaching and Learning through Chemistry Education Research: A Look to the Future · Journal of Chemical Education · 1999 · 324 citations
- A Guided-Inquiry General Chemistry Course · Journal of Chemical Education · 1999 · 280 citations
- Intersensory facilitation of reaction time: Energy summation or preparation enhancement? · Psychological Review · 1973 · 263 citations
- A universal system for digitization and automatic execution of the chemical synthesis literature · Science · 2020 · 260 citations
- Evidence for the Importance of Laboratory Courses · Journal of Chemical Education · 2019 · 248 citations
Most recent work
- Chasing nature’s anion binders · Chem · 2026
- Acetone recycling: a case study in the undergraduate teaching laboratory · RSC Sustainability · 2026
- Colourful chemistry of anthocyanins: a tutorial review of applications of anthocyanins in school and university teaching · RSC Sustainability · 2026
- RECOMPENSE: a student-led open science initiative for sustainable polystyrene waste upcycling in academic labs · RSC Sustainability · 2026
- Citizen analytical chemistry: building a participatory and shared science through global data generation · RSC Sustainability · 2026
- Shining Light on Halide Perovskites: Teaching Analytical Chemistry Using Flexible, Inquiry-Based Experiments · Journal of Chemical Education · 2026
- Investigating Chemistry’s Potential Roles in the Life Cycle of Plastics – An Outreach Laboratory Activity for High School Students · Journal of Chemical Education · 2026
- Graphene Quantum Dots as a Teaching Platform: A Computational Module for Exploring Structure–Property–Function Relationships · Journal of Chemical Education · 2026
- A user's guide to your first self-driving liquid handling lab · Digital Discovery · 2026
- Spectrometer Assembly and Python-Based Data Science Lab on the Reduction Kinetics of Methylene Blue · Journal of Chemical Education · 2026
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