Research gap analyses
Page 7 of 19, ordered by evidence strength.
Showing 361–420 of 1,136 gap analyses · page 7 of 19
- However, little is known about the role of agricultural cooperatives in accelerating the adoption of improved agricultural technologies.
However, little is known about the role of agricultural cooperatives in accelerating the adoption of improved agricultural technologies.
Agriculture · 3 papers · avg 2021 · weak evidence - Cattle-centered food systems are not limited to animals, pasture, slaughter, or consumer choice.
Cattle-centered food systems are not limited to animals, pasture, slaughter, or consumer choice.
Agriculture · 3 papers · avg 2022.7 · weak evidence - However, inconsistent results have been obtained with regard to major crops such as rice and wheat in rice–wheat rotation systems of China.
However, inconsistent results have been obtained with regard to major crops such as rice and wheat in rice–wheat rotation systems of China.
Agriculture · 3 papers · avg 2022.7 · weak evidence - However, there are few studies on the interaction between planting density and nitrogen fertilizer under drip fertigation.
However, there are few studies on the interaction between planting density and nitrogen fertilizer under drip fertigation.
Agriculture · 3 papers · avg 2023.7 · weak evidence - Phosphorus (P), an essential yet often limiting nutrient in agroecosystems, may be sensitive to MPs inputs, while the mechanisms governing MPs‐induced alterations in soil P‐cycling remain poorly under
Phosphorus (P), an essential yet often limiting nutrient in agroecosystems, may be sensitive to MPs inputs, while the mechanisms governing MPs‐induced alterations in soil P‐cycling remain poorly understood.
Agriculture · 3 papers · avg 2022.3 · weak evidence - Abstract Limited information is available on the influence of a one‐time application of controlled‐release nitrogen fertilizer (CRNF) in improving both yield and quality of rice.
Abstract Limited information is available on the influence of a one‐time application of controlled‐release nitrogen fertilizer (CRNF) in improving both yield and quality of rice.
Agriculture · 3 papers · avg 2023.7 · weak evidence - Although biostimulants have attracted attention for sustainable agricultural systems, their efficacy remains poorly understood.
Although biostimulants have attracted attention for sustainable agricultural systems, their efficacy remains poorly understood.
Agriculture · 3 papers · avg 2025.7 · weak evidence - However, its potential as a forage source remains underexplored, particularly during the regrowth phase, which is critical for sustainable feed production.
However, its potential as a forage source remains underexplored, particularly during the regrowth phase, which is critical for sustainable feed production.
Agriculture · 3 papers · avg 2026 · weak evidence - Mechanisms influencing retention, biogeochemical cycling, and release of legacy mercury within soils of forests and wetlands remain poorly understood.
Mechanisms influencing retention, biogeochemical cycling, and release of legacy mercury within soils of forests and wetlands remain poorly understood.
Agriculture · 3 papers · avg 2019.3 · weak evidence - Yet ecosystem disservices are often underreported in the scientific literature, potentially biasing how agroecosystem functioning is understood.
Yet ecosystem disservices are often underreported in the scientific literature, potentially biasing how agroecosystem functioning is understood.
Agriculture · 3 papers · avg 2025.7 · weak evidence - However, no consensus exists regarding its definition, which is reflected by the early state of agroecology as a science.
However, no consensus exists regarding its definition, which is reflected by the early state of agroecology as a science.
Agriculture · 3 papers · avg 2024 · weak evidence - The promising results indicate that further work on greater number of piles may lead to a better understanding of pile–soil interaction and a more accurate design process.
The promising results indicate that further work on greater number of piles may lead to a better understanding of pile–soil interaction and a more accurate design process.
Agriculture · 3 papers · avg 2023 · weak evidence - However, it should be investigated the influences of dams on the groundwater through lower basin.
However, it should be investigated the influences of dams on the groundwater through lower basin.
Agriculture · 3 papers · avg 2020.3 · weak evidence - Further studies on various agroecological conditions such as soil types, vegetation and climate will provide further insights into the effective use of biomass ash.
Further studies on various agroecological conditions such as soil types, vegetation and climate will provide further insights into the effective use of biomass ash.
Agriculture · 3 papers · avg 2021 · weak evidence - There are very few studies on mapping the changes in soil grain size and erodible fraction due to wind erosion.
There are very few studies on mapping the changes in soil grain size and erodible fraction due to wind erosion.
Agriculture · 3 papers · avg 2022 · weak evidence - The effect of volume of endodontic irrigants on the microhardness of root canal dentin has not been studied.
The effect of volume of endodontic irrigants on the microhardness of root canal dentin has not been studied.
Agriculture · 3 papers · avg 2019.3 · weak evidence - However, little is known regarding the effects of permafrost collapse in upland landscapes on the biogeochemical processes that affect carbon balance.
However, little is known regarding the effects of permafrost collapse in upland landscapes on the biogeochemical processes that affect carbon balance.
Agriculture · 3 papers · avg 2018.7 · weak evidence - Recent studies suggest that molecular-scale organization of chromatin near the nuclear periphery (lamina-associated domains, LADs) affects gene regulation, providing transciptional supression, but the
Recent studies suggest that molecular-scale organization of chromatin near the nuclear periphery (lamina-associated domains, LADs) affects gene regulation, providing transciptional supression, but the biophysical mechanisms of supression be
Biology · 3 papers · avg 2025.7 · weak evidence - Even for lipid nanoparticles (LNPs)--the most advanced RNA delivery platform--stereochemical effects are rarely investigated and, when considered, are typically limited to the ionizable lipid rather t
Even for lipid nanoparticles (LNPs)--the most advanced RNA delivery platform--stereochemical effects are rarely investigated and, when considered, are typically limited to the ionizable lipid rather than the overall stereochemical identity
Biology · 3 papers · avg 2026 · weak evidence - The computational study of immune cell trafficking and the tumour microenvironment is a rapidly advancing field, propelled forward by developments in artificial intelligence, single-cell omics technologi
The computational study of immune cell trafficking and the tumour microenvironment is a rapidly advancing field, propelled forward by developments in artificial intelligence, single-cell omics technologies, and increasingly sophisticated compu
Biology · 3 papers · avg 2026 · weak evidence - This systematic review focusing on CM-sEVs revealed that Ldb3, CD172a, and Ambra1 are potential specific molecular markers of CM-sEVs. These markers can be used to trace the origin of CM-sEVs and serv
This systematic review focusing on CM-sEVs revealed that Ldb3, CD172a, and Ambra1 are potential specific molecular markers of CM-sEVs. These markers can be used to trace the origin of CM-sEVs and serve as potential diagnostic biomarkers for
Biology · 3 papers · avg 2026 · weak evidence - CRISPR screens have mapped the core circuitry by which T cells achieve anti-tumor activity, repeatedly converging on JAK/STAT cytokine signaling, proximal and distal TCR/NF-kB pathways including RNA s
CRISPR screens have mapped the core circuitry by which T cells achieve anti-tumor activity, repeatedly converging on JAK/STAT cytokine signaling, proximal and distal TCR/NF-kB pathways including RNA stability programs, and transcriptional/e
Biology · 3 papers · avg 2026 · weak evidence - Abstract Despite the thousands of genes implicated in age-related phenotypes, effective interventions for aging remain elusive, due to the multifactorial nature of longevity and the interconnectedness
Abstract Despite the thousands of genes implicated in age-related phenotypes, effective interventions for aging remain elusive, due to the multifactorial nature of longevity and the interconnectedness of molecular components involved.
Biology · 3 papers · avg 2026 · weak evidence - Neurodegenerative diseases are closely linked to aberrant protein aggregation arising from failures in cellular proteostasis, yet the physical determinants governing transitions between soluble states
Neurodegenerative diseases are closely linked to aberrant protein aggregation arising from failures in cellular proteostasis, yet the physical determinants governing transitions between soluble states, liquid liquid phase separation (LLPS),
Biology · 3 papers · avg 2026 · weak evidence - Abstract The bacterial genus Endozoicomonas is prevalent and abundant in the microbiome of many corals, but the combination of environmental and host factors shaping its distribution remains uncertain
Abstract The bacterial genus Endozoicomonas is prevalent and abundant in the microbiome of many corals, but the combination of environmental and host factors shaping its distribution remains uncertain.
Biology · 3 papers · avg 2026 · weak evidence - While recent co-folding models such as AlphaFold-3 achieve accurate structure prediction, they fail to generalize to underexplored binding interfaces - systematically misplacing ligands, particularly
While recent co-folding models such as AlphaFold-3 achieve accurate structure prediction, they fail to generalize to underexplored binding interfaces - systematically misplacing ligands, particularly for allosteric or structurally novel tar
Biology · 3 papers · avg 2025.3 · weak evidence - Biofilm formation by Helicobacter pylori is a major driver of antibiotic tolerance and treatment failure, yet the signaling pathways that trigger biofilm development under sub-inhibitory antibiotic pr
Biofilm formation by Helicobacter pylori is a major driver of antibiotic tolerance and treatment failure, yet the signaling pathways that trigger biofilm development under sub-inhibitory antibiotic pressure remain poorly understood.
Biology · 3 papers · avg 2016.3 · weak evidence - However, there is scarce scholarship on the phenomenon of armed groups shifting their conflict-waging strategies from violent to nonviolent means, especially in contexts which cannot be resolved by fo
However, there is scarce scholarship on the phenomenon of armed groups shifting their conflict-waging strategies from violent to nonviolent means, especially in contexts which cannot be resolved by force but are also ‘unripe’ for convention
Biology · 3 papers · avg 2011.7 · weak evidence - Studies that evaluate this hypothesis have used different approaches to test whether invasive populations allocate fewer resources to defense and more to growth and competitive ability than do source
Studies that evaluate this hypothesis have used different approaches to test whether invasive populations allocate fewer resources to defense and more to growth and competitive ability than do source populations, with mixed results.
Biology · 3 papers · avg 2021.7 · weak evidence - Yet longitudinal evidence that can substantiate claims of media’s increased reliance on this “subsidized content” is scarce, and equally scarce is literature about the reliance of the news agency—a ke
Yet longitudinal evidence that can substantiate claims of media’s increased reliance on this “subsidized content” is scarce, and equally scarce is literature about the reliance of the news agency—a key factor in the news production process—
Biology · 3 papers · avg 2016.7 · weak evidence - Abstract Microclimates within microcosms are often stated to shelter occupants from adverse conditions, yet our limited knowledge narrows our ability to estimate the vulnerability to warming of specie
Abstract Microclimates within microcosms are often stated to shelter occupants from adverse conditions, yet our limited knowledge narrows our ability to estimate the vulnerability to warming of species exploiting them.
Biology · 3 papers · avg 2026 · weak evidence - Although plant–mycorrhizal fungi associations play critical roles in maintaining species diversity within forest communities, the influence of tree ontogeny in mediating these effects on species diver
Although plant–mycorrhizal fungi associations play critical roles in maintaining species diversity within forest communities, the influence of tree ontogeny in mediating these effects on species diversity remains poorly understood.
Biology · 3 papers · avg 2025 · weak evidence - CONCLUSIONS: Together, the findings offer researchers ample reason to further investigate the contribution of the catecholamine and opioid systems, and their associated genomic variants, to the still
CONCLUSIONS: Together, the findings offer researchers ample reason to further investigate the contribution of the catecholamine and opioid systems, and their associated genomic variants, to the still poorly understood experience of FM.
Biology · 3 papers · avg 2020.7 · weak evidence - Urbanization, biodiversity, and conservation: The impacts of urbanization on native species are poorly studied, but educating a highly urbanized human population about these impacts can greatly improv
Urbanization, biodiversity, and conservation: The impacts of urbanization on native species are poorly studied, but educating a highly urbanized human population about these impacts can greatly improve species conservation in all ecosystems
Biology · 3 papers · avg 2026 · weak evidence - Few studies have considered whether the consequences associated with parental incarceration extend beyond the children who experience the event, and whether the influence of parental incarceration var
Few studies have considered whether the consequences associated with parental incarceration extend beyond the children who experience the event, and whether the influence of parental incarceration varies by the context in which it occurs.
Biology · 3 papers · avg 2016.7 · weak evidence - Although social disorganization theory hypothesizes that neighborhood characteristics influence youth delinquency, the impact of neighborhood disadvantage on adolescent substance use and racial/ethnic
Although social disorganization theory hypothesizes that neighborhood characteristics influence youth delinquency, the impact of neighborhood disadvantage on adolescent substance use and racial/ethnic differences in this relationship have n
Biology · 3 papers · avg 2012.3 · weak evidence - Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive types of cancer and chemotherapy resistant cancer, in the development of which poorly studied cancer stem cells (CSC) and mesenchy
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive types of cancer and chemotherapy resistant cancer, in the development of which poorly studied cancer stem cells (CSC) and mesenchymal stem cells (MSC) are of great import
Biology · 3 papers · avg 2023.7 · weak evidence - Abstract Although there is an increased understanding of fire's role in maintaining grassland ecosystems, few studies on vegetation develops after a fire disturbance has been reported in arid perennia
Abstract Although there is an increased understanding of fire's role in maintaining grassland ecosystems, few studies on vegetation develops after a fire disturbance has been reported in arid perennial grasslands on the Loess Plateau.
Biology · 3 papers · avg 2016.3 · weak evidence - Plastic pollution is ubiquitous in the environment, with microplastics (particles < 5 mm) a worldwide emergent contaminant of concern; however, no studies have explored historical patterns in fresh
Plastic pollution is ubiquitous in the environment, with microplastics (particles < 5 mm) a worldwide emergent contaminant of concern; however, no studies have explored historical patterns in freshwater macroinvertebrates in connection t
Biology · 3 papers · avg 2025.7 · weak evidence - Host-associated microbiomes play vital roles in organismal health, ecological interactions, and evolution, yet little is known about how microbial communities shift during the transition from aquatic
Host-associated microbiomes play vital roles in organismal health, ecological interactions, and evolution, yet little is known about how microbial communities shift during the transition from aquatic to increasingly terrestrial habitats.
Biology · 3 papers · avg 2026 · weak evidence - Effective plant immunity requires precise spatial coordination of immune responses across cell-types to restrict pathogens while preventing tissue damage, yet the intracellular pathways that organize
Effective plant immunity requires precise spatial coordination of immune responses across cell-types to restrict pathogens while preventing tissue damage, yet the intracellular pathways that organize this spatial architecture remain unknown
Biology · 3 papers · avg 2026 · weak evidence - Gender segregated peer networks during middle childhood have been highlighted as important for explaining later sex differences in behaviour, yet few studies have examined the structural composition o
Gender segregated peer networks during middle childhood have been highlighted as important for explaining later sex differences in behaviour, yet few studies have examined the structural composition of these networks and their implications.
Biology · 3 papers · avg 2009 · weak evidence - Abstract To date, the unifying pathogenesis, or etiology, of autism spectrum disorders ( ASDs ) and Williams syndrome ( WS ) remains unknown, partly because of the broad variation of phenotypes and th
Abstract To date, the unifying pathogenesis, or etiology, of autism spectrum disorders ( ASDs ) and Williams syndrome ( WS ) remains unknown, partly because of the broad variation of phenotypes and the heterogeneity of syndrome expression.
Biology · 3 papers · avg 2018.7 · weak evidence - Despite the fact that caregiving related issues are well researched in the field of family gerontology, the developmental experiences of grandchildren caregivers and the meanings of their caregiving e
Despite the fact that caregiving related issues are well researched in the field of family gerontology, the developmental experiences of grandchildren caregivers and the meanings of their caregiving experiences have not been explored.
Biology · 3 papers · avg 2010.3 · weak evidence - It is well known that the stacking of thylakoids and the lateral macro-organization of the pigment–protein complexes in the membrane are interrelated (reviewed by Musta´rdy and Garab 2003; Dekker and
It is well known that the stacking of thylakoids and the lateral macro-organization of the pigment–protein complexes in the membrane are interrelated (reviewed by Musta´rdy and Garab 2003; Dekker and Boekema 2005) but dgd1 is poorly charact
Biology · 3 papers · avg 2026 · weak evidence - Temporal trends in declining sperm quality are documented globally, but the specific contribution of ultra-processed food consumption to this trend needs further epidemiological investigation.
Temporal trends in declining sperm quality are documented globally, but the specific contribution of ultra-processed food consumption to this trend needs further epidemiological investigation.
Biology · 3 papers · avg 2024.7 · weak evidence - The molecular dynamics simulations were performed using AlphaFold-predicted protein structure rather than experimentally resolved crystal structures, which may affect accuracy of binding predictions.
The molecular dynamics simulations were performed using AlphaFold-predicted protein structure rather than experimentally resolved crystal structures, which may affect accuracy of binding predictions.
Biology · 3 papers · avg 2026 · weak evidence - Technical and regulatory challenges persist in translating exosome-based therapeutics from bench to clinic.
Technical and regulatory challenges persist in translating exosome-based therapeutics from bench to clinic.
Biology · 3 papers · avg 2024.7 · weak evidence - MD simulations were limited to 100 ns duration, which may not be sufficient to capture long-timescale conformational changes or binding kinetics relevant to drug efficacy.
MD simulations were limited to 100 ns duration, which may not be sufficient to capture long-timescale conformational changes or binding kinetics relevant to drug efficacy.
Biology · 3 papers · avg 2026 · weak evidence - There is a need to examine how assumptions and advocacy shape scientific interpretation in conservation biology, suggesting a gap in understanding the epistemological foundations of conservation pract
There is a need to examine how assumptions and advocacy shape scientific interpretation in conservation biology, suggesting a gap in understanding the epistemological foundations of conservation practice.
Biology · 3 papers · avg 2021 · weak evidence - Plant synthetic biology requires building intellectual and physical infrastructure to rapidly design and assemble synthetic genetic systems in plants, but the paper does not specify what standardized
Plant synthetic biology requires building intellectual and physical infrastructure to rapidly design and assemble synthetic genetic systems in plants, but the paper does not specify what standardized assembly methods, plant-specific biobric
Biology · 3 papers · avg 2016.2 · weak evidence - Field-scale application and bioremediation of heavily contaminated soils using this fungal consortium with biostimulation strategy requires validation beyond laboratory conditions.
Field-scale application and bioremediation of heavily contaminated soils using this fungal consortium with biostimulation strategy requires validation beyond laboratory conditions.
Biology · 3 papers · avg 2025 · weak evidence - Emphasizing green chemistry, using non-toxic PEG/water as a solvent aligns with efforts to reduce hazardous waste without study enhances compromising performance. The versatility of the Fe3O4@SiO2- Do
Emphasizing green chemistry, using non-toxic PEG/water as a solvent aligns with efforts to reduce hazardous waste without study enhances compromising performance. The versatility of the Fe3O4@SiO2- Dop/Phen-Pd (0) catalyst offers potential
Chemistry · 3 papers · avg 2025.3 · weak evidence - The evolution of smart polymer systems is moving rapidly from proof-of-concept lab studies to real-world biomedical applications, driven by cross-disciplinary innovation in materials science, biotechn
The evolution of smart polymer systems is moving rapidly from proof-of-concept lab studies to real-world biomedical applications, driven by cross-disciplinary innovation in materials science, biotechnology, and data intelligence. The next g
Chemistry · 3 papers · avg 2026 · weak evidence - The synthesis of photocatalysts with both broad light absorption and efficient charge separation is significant for a high solar energy conversion, which still remains to be a challenge.
The synthesis of photocatalysts with both broad light absorption and efficient charge separation is significant for a high solar energy conversion, which still remains to be a challenge.
Chemistry · 3 papers · avg 2025.3 · weak evidence - Most catalysts are metal‐based, and metal‐free catalysts with high nitrate‐to‐ammonia conversion activity are rarely reported.
Most catalysts are metal‐based, and metal‐free catalysts with high nitrate‐to‐ammonia conversion activity are rarely reported.
Chemistry · 3 papers · avg 2023.3 · weak evidence - However, carbon-based electrocatalysts that are capable of generating H2O2 at industrial-level current densities (>300 mA cm−2) with high selectivity and long-term stability remain to be discovered.
However, carbon-based electrocatalysts that are capable of generating H2O2 at industrial-level current densities (>300 mA cm−2) with high selectivity and long-term stability remain to be discovered.
Chemistry · 3 papers · avg 2024 · weak evidence - The operational lifetimes of n-i-p perovskite solar cells have been limited by the layer-to layer ion diffusion in the perovskite/hole-transport layer heterojunction.
The operational lifetimes of n-i-p perovskite solar cells have been limited by the layer-to layer ion diffusion in the perovskite/hole-transport layer heterojunction.
Chemistry · 3 papers · avg 2025.3 · weak evidence - Abstract Alkaline hydrogen evolution reaction (HER) has great potential in practical hydrogen production but is still limited by the lack of active and stable electrocatalysts.
Abstract Alkaline hydrogen evolution reaction (HER) has great potential in practical hydrogen production but is still limited by the lack of active and stable electrocatalysts.
Chemistry · 3 papers · avg 2024 · weak evidence - The major limitations of the Fenton process are the working pH range (2–5) and the high cost of H2O2.
The major limitations of the Fenton process are the working pH range (2–5) and the high cost of H2O2.
Chemistry · 3 papers · avg 2022.7 · weak evidence